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目的 :探讨急性下壁心肌梗死 (MI)时前壁 V1~ 3 和 V4~ 6 导联 ST段压低的临床意义。方法 :回顾性分析 5 9例首发急性下壁 MI患者的心电图和冠状动脉造影资料。分为 3组 :组 1:急性下壁 MI不伴前壁导联 ST段压低 (30例 ) ;组 2 :急性下壁 MI伴前壁 V1~ 3导联 ST段压低 (15例 ) ;组 3:急性下壁 MI伴前壁 V4~ 6 导联 ST段压低 (14例 )。结果 :组 2的左旋支狭窄 (≥ 70 % )例数明显多于另外两组 (6 0 % vs 2 7%、2 8% ,P <0 .0 5 ) ,其多支血管病变较多 (10 .0 %、2 8.6 % vs6 6 .7% ,P<0 .0 5 ) ,肌酸激酶同工酶峰值较高 [(173.78± 5 8.83) U/ L 、(16 4.2 2± 38.12 ) U/ L vs(2 39.6 5± 45 .34) U/ L,P <0 .0 5 ],左室射血分数较低 [(6 1± 7) %、(5 6± 5 ) % vs(4 5±10 ) % ,P <0 .0 5 ]。组 1与组 3相比 ,两者的各种参数差异无显著性意义 (P >0 .0 5 )。结论 :急性下壁 MI伴 V1~ 3导联 ST段压低提示和左旋支的病变有关 ,其 MI面积较大、射血分数较低。
Objective: To investigate the clinical significance of ST segment depression in anterior wall V1 ~ 3 and V4 ~ 6 leads in acute inferior myocardial infarction (MI). Methods: ECG and coronary angiography data of 59 patients with acute inferior MI were retrospectively analyzed. Group 1: acute inferior wall MI without anterior ST segment depression (30 cases); group 2: acute inferior wall MI with anterior ST segment depression of V1 ~ 3 lead (15 cases); group 3: Acute inferior MI with anterior wall V4 ~ 6 lead ST segment depression (14 cases). Results: The number of left circumflex artery stenosis (≥ 70%) in group 2 was significantly higher than that in the other two groups (60% vs 27%, 28%, P <0. 05) The peak of creatine kinase isoenzymes was higher (173.78 ± 5 8.83) U / L, (16 4.2 2 ± 38.12) U / L vs (39.6 ± 45.34) U / L, P <0.05), lower left ventricular ejection fraction [(6 1 ± 7)%, (56 ± 5)% vs 5 ± 10)%, P <0. 05]. There was no significant difference between group 1 and group 3 (P> 0.05). Conclusion: It is suggested that the acute inferior wall MI with ST segment depression in V1 ~ 3 lead is related to the lesion of left circumflex artery. The MI area is larger and the ejection fraction is lower.