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目的探讨急性冠状动脉综合征合并肾功能不全30例支架术治疗分析。方法 30例急性冠状动脉综合征合并肾功能不全患者作为观察组,将同期30例急性冠状动脉综合征肾功能正常患者作为对照组,均采用支架术治疗。比较两组患者的血管特征、手术各项指标、肾功能情况、不良事件发生率等。结果观察组冠脉病变范围及病变程度均明显较对照组重,差异有统计学意义(P<0.05);两组患者手术成功率、术中植入支架直径、支架长度、支架扩张最高压力、术后残余狭窄等比较,差异均无统计学意义(P>0.05);观察组术前、术后48、72 h及1个月后血清肌酐(Scr)明显高于对照组,差异有统计学意义(P<0.05);观察组心血管事件发病率明显高于对照组,差异有统计学意义(P<0.05)。结论急性冠状动脉综合征合并肾功能不全近期疗效显著,但其病变程度重,远期心血管事件发病率高。临床应密切监视患者病情变化,以防发生不良预后。
Objective To investigate the treatment of 30 cases of acute coronary syndrome with renal insufficiency. Methods Thirty patients with acute coronary syndrome and renal dysfunction were selected as the observation group. Thirty patients with normal renal function in the group of acute coronary syndrome were selected as the control group. All patients were treated with stenting. Vascular characteristics, operation indexes, renal function and incidence of adverse events were compared between the two groups. Results The extent and severity of coronary lesions in the observation group were significantly heavier than those in the control group (P <0.05). The success rate of operation, the diameter of stents implanted, the length of stent, the maximum pressure of stent expansion, Postoperative residual stenosis and other comparison, the difference was not statistically significant (P> 0.05); observation group before and after 48,72 h and 1 month after the serum creatinine (Scr) was significantly higher than the control group, the difference was statistically significant (P <0.05). The incidence of cardiovascular events in the observation group was significantly higher than that in the control group (P <0.05). Conclusion Acute coronary syndrome with renal insufficiency has a significant short-term curative effect, but its severity is severe and the incidence of long-term cardiovascular events is high. Clinically, the patient’s condition should be closely monitored to prevent adverse prognosis.