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肺癌的正确分型对治疗和予后的判断至关重要。肺癌由于具有细胞类型的混合和多形性的特点,光镜分型标准不能对肺癌作出正确的分型,直接影响疗效和予后的判断。近年来肺癌采用超微结构分型,虽提高其分型的准确性,但由于取材局限、需要特殊设备和组织处理,国内目前尚难普遍应用。晚近研究表明,免疫组比可作为肺癌诊断分型的辅助手段。本文对50例肺癌进行了光镜、电镜、角蛋白和CEA的PAP染色,观察和讨论角蛋白和CEA在各型肺癌细胞内的定位分布及其在肺癌分型的意义。
The correct classification of lung cancer is crucial for treatment and later judgment. Because lung cancer has the characteristics of cell type mixture and pleomorphism, light microscope classification criteria cannot accurately classify lung cancer, directly affecting efficacy and subsequent judgment. In recent years, the use of ultra-structural classification of lung cancer, although improving the accuracy of its classification, but due to the limitations of materials, the need for special equipment and tissue processing, the domestic is still difficult to universal application. Recent studies have shown that the immune group ratio can be used as an adjunct to lung cancer diagnosis. In this paper, PAP staining of light microscopy, electron microscopy, keratin, and CEA was performed on 50 cases of lung cancer. The localization and distribution of keratin and CEA in various types of lung cancer cells and their significance in lung cancer classification were observed and discussed.