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氟哌酸(Norfloxacin,简称NFLX)、氟嗪酸(ofloxacin,简称OFLX)、氟啶酸(Enoxacin,简称ENX)等新吡啶酮酸类合成抗菌剂,其应用范围扩大到呼吸器官感染,具有很高的有用性,其中氟啶酸(ENX)对慢性呼吸道感染有效率高,但当与茶碱同用时,可使茶碱血浓度显著升高,致使副反应发生率增加.对5例健康成人男子所进行的试验表明,当同时单次口服300mg茶碱和200mg氟嗪酸或氟啶酸时,无论哪个药物均无明显变化.但当预先口服200mg茶碱/次、一天二次、连续四天,在血浓度稳定时,同时
Norpyloxacin (NFLX), ofloxacin (OFLX), and neoxypyridin (ENX) are widely used in the treatment of respiratory infections. High usefulness, of which the effective rate of nifedipine (ENX) on chronic respiratory infections, but when used with theophylline, theophylline blood concentration can be significantly increased, resulting in increased incidence of side effects in 5 healthy adults Men’s trials showed that when both single oral 300mg theophylline and 200mg of triflusal or uridine acid, no matter which drug did not change significantly, but when premedication 200mg theophylline / time, twice a day, four consecutive Day, when the blood concentration is stable, at the same time