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用透射电镜观察了一组18例肿瘤细胞胞浆中有微丝结构的软组织恶性肿瘤,电镜观察结果与光镜诊断不同,主要发生在纤维肉瘤、平滑肌肉瘤和恶性纤维组织细胞瘤中。肿瘤细胞膜下的具有密体的带状微丝可见于上述各种肿瘤中。一些肿瘤细胞也具有特征性的微丝结构。说明上述肿瘤的细胞成分有重叠。提出肿瘤的分类应主要依据大多数肿瘤细胞的分化方向来确定而不是臆测其组织发生和细胞来源。按此方法分类将会出现更多的纤维组织细胞瘤、肌纤维母细胞瘤和肌纤维组织细胞瘤的诊断。
Transmission electron microscopy was used to observe the malignant tumors of the soft tissue with microfilaments in the cytoplasm of a group of 18 tumors. The results of electron microscopy were different from those of light microscopy. They mainly occurred in fibrosarcoma, leiomyosarcoma, and malignant fibrous histiocytoma. Banded microfilaments under the tumor cell membrane can be found in the various tumors described above. Some tumor cells also have a characteristic microfilament structure. It shows that there are overlaps in the cellular components of these tumors. It is proposed that the classification of tumors should be based primarily on the direction of differentiation of most tumor cells rather than speculation as to their histogenesis and cell origin. Classification by this method will result in the diagnosis of more fibrous histiocytoma, myofibroblastic, and myofibroblastomas.