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目的:探讨短暂性脑缺血发作(transient ischemia attach,TIA)患者血脂水平对预后的影响及其临床意义。方法:回顾性分析以2009年最新定义为诊断标准的我院TIA患者62例,根据ABCD2评分进行危险分级。其中,低危组(0~3分)患者16例、中危组(4~5分)患者20例,高危组(6~7分)患者26例,比较三组患者血脂水平的差异及其预后效果的影响。结果:三组患者中血脂水平从高到低依次为:高危组、中危组与低危组,其中高危组血脂水平与其它两组患者血脂水平的差异均有统计学意义(P<0.05),但中危组与低危组间差异无统计学意义(P>0.05)。低、中危组患者血脂平均水平随ABCD2分值增高呈轻度上升趋势,高危组患者血脂平均水平随ABCD2分值明显增高。血脂水平越高其预后效果相对越差。结论:血脂水平与TIA患者ABCD2评分呈正相关的趋势,而与预后效果呈负相关的趋势。
Objective: To investigate the effect of serum lipid level on prognosis in patients with transient ischemia reperfusion (TIA) and its clinical significance. Methods: A retrospective analysis of 62 cases of TIA in our hospital, which was newly defined as the diagnostic criteria in 2009, was carried out according to the ABCD2 score. Among them, there were 16 patients in the low-risk group (0-3), 20 in the moderate-risk group (4-5) and 26 in the high-risk group (6-7). The differences of the blood lipid levels among the three groups were compared Effect of prognosis. Results: The levels of serum lipids in high-risk group, middle-risk group and low-risk group from high to low were significant differences among the three groups (P <0.05) , But there was no significant difference between the moderate-risk group and the low-risk group (P> 0.05). In the low and intermediate risk groups, the average level of blood lipid increased slightly with the increase of ABCD2, and the level of blood lipid in high risk group increased significantly with the score of ABCD2. The higher the level of blood lipids, the poorer the prognosis. Conclusion: There is a positive correlation between serum lipid level and ABCD2 score in TIA patients, but negatively correlated with prognosis.