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白细胞间介素(Interleukin,IL)是近年研究较多和引人注目的一类淋巴因子。这方面的研究,有助于对免疫应答、免疫调控机制、免疫调节剂的药理及一些免疫性疾病病因的进一步阐明。一、IL与免疫应答人白细胞提出的转移因子(TF)能刺激Mφ生产IL_1,因为TF能提高Mφ内cGMP水平。外源性cGMP及其它cGMP诱生剂也可刺激Mφ释放IL_l。IL_1是产生IL_2的第二信号。此外,IL_1还可促进胸腺细胞增殖;促进淋巴
Interleukin (IL) is a type of lymphokine that has been studied in recent years and attracts attention. Research in this area will help further elucidate the immune response, immune regulation mechanisms, pharmacology of immunomodulators, and the causes of some immune diseases. First, IL and immune response Transfer factor (TF) proposed by human leukocytes stimulates Mφ to produce IL_1, because TF can increase the level of cGMP within Mφ. Exogenous cGMP and other cGMP-inducing agents also stimulate the release of IL-1 from Mφ. IL_1 is the second signal that produces IL_2. In addition, IL_1 can also promote thymocyte proliferation; promote lymphatic