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医药产业是一个高投入、高产出、高风险的行业。高新技术的不断发展,如组合技术(将化学合成、电脑设计和机器人筛选合为一体)、计算化学(药物分子设计、计算机图解、同系性或相似性模型制作)、靶分子生物学等在新药开发中的应用,推动着新药开发进入全新的时代。全世界每年首次上市的新化学实体有40～50个,新药的不断上市推进了药品市场增长,1996年世界药品市场增长率约为8％,药品市场销售额达3086亿美元,1997年全世界10个领先大市场的药品销售总额总计增长6％,总额达到1655.3亿美元,这其中销售额居世界前10位的10家制药跨国公司的销售额总和达878.2亿美元,支撑着世界药品市场的半壁江山。制药跨国公司的发展速度很大程度上制约着世界药品市场的成长,综观这些公司的发展,主要经历了下文所述
The pharmaceutical industry is a high-input, high-output, high-risk industry. The continuous development of high technology, such as combinatorial technology (combination of chemical synthesis, computer design and robotic screening), computational chemistry (drug molecule design, computer graphics, homology or similarity modeling), target molecule biology, etc. The application in development promotes the development of new drugs into a new era. There are 40 to 50 new chemical entities listed for the first time in the world every year. The continued listing of new drugs has boosted the growth of the pharmaceutical market. In 1996, the growth rate of the world pharmaceutical market was about 8%, and the pharmaceutical market sales reached US$ 308.6 billion. The total sales of drugs in 10 leading markets increased by 6% in total to a total of 165.53 billion U.S. dollars. The total sales of the 10 pharmaceutical multinational companies with the top ten sales in the world amounted to US$ 87.82 billion, supporting the world pharmaceutical market. Half of the country. The speed of development of pharmaceutical multinationals has largely constrained the growth of the world pharmaceutical market. Looking at the development of these companies, they have experienced the following