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目的分析甲泼尼龙冲击疗法应用在急性脊髓炎治疗中的有效性。方法 80例急性脊髓炎患者,按随机数字法分为实验组和对照组,各40例。实验组采用甲泼尼龙冲击疗法治疗,对照组采用常规治疗。比较两组治疗总有效率及脊髓神经功能恢复情况。结果实验组患者治疗显效32例,有效6例,无效2例,治疗总有效率为95.0%(38/40);对照组患者治疗显效20例,有效9例,无效11例,治疗总有效率为72.5%(29/40),实验组患者治疗总有效率高于对照组患者,差异具有统计学意义(P<0.05)。实验组肌力改善2级时间为(4.8±1.2)d,排尿恢复时间为(9.4±2.6)d,自行下地行走时间为(14.3±1.4)d;对照组肌力改善2级时间为(9.7±1.9)d,排尿恢复时间为(18.3±2.7)d,自行下地行走时间为(22.3±2.6)d。实验组肌力改善2级时间、排尿恢复时间、自行下地行走时间均短于对照组,差异具有统计学意义(P<0.05)。结论甲泼尼龙冲击疗法可改善急性脊髓炎患者的脊髓神经功能,疗效肯定,临床推广价值更高。
Objective To analyze the effectiveness of methylprednisolone in the treatment of acute myelitis. Methods Eighty patients with acute myelitis were divided into experimental group and control group according to random number method, 40 cases in each. The experimental group was treated with methylprednisolone impact therapy and the control group with conventional therapy. The total effective rate of treatment and the recovery of spinal nerve function were compared between the two groups. Results In the experimental group, 32 cases were treated effectively, 6 cases were effective and 2 cases were ineffective. The total effective rate was 95.0% (38/40). In the control group, 20 cases were treated effectively, 9 cases were effective and 11 cases were ineffective. The total effective rate Was 72.5% (29/40). The total effective rate of treatment group was higher than that of control group, the difference was statistically significant (P <0.05). In the experimental group, the improvement of muscular strength was (4.8 ± 1.2) days, the urination recovery time was (9.4 ± 2.6) days and walking time was (14.3 ± 1.4) ± 1.9) d, urination recovery time was (18.3 ± 2.7) d, walking on their own time was (22.3 ± 2.6) d. The experimental group improved 2 times of muscle strength, urination recovery time, go walking on their own shorter than the control group, the difference was statistically significant (P <0.05). Conclusion Methylprednisolone impact therapy can improve spinal cord nerve function in patients with acute myelitis. The curative effect is definite and the value of clinical popularization is higher.