肌红蛋白(myoglobin)是能够进行可逆性氧化的一种蛋白质。广泛分布于软体动物和人类,其分子量约17,800。它只有一个(珠蛋白)多肽链和一个辅基组(血红素)所组成。一些分化较差的横纹肌肉瘤用HE染色常常不能确定其组织起源,给外科病理诊断带来困难。由于肌红蛋白只存在于横纹肌,抗肌红蛋白的抗体对于横纹肌源性的肿瘤是个很好的标记。 Myoglobin is a protein that is capable of reversible oxidation. It is widely distributed in mollusks and humans and has a molecular weight of approximately 17,800. It consists of only one (globin) polypeptide chain and one prosthetic group (hemoglobin). Some of the poorly differentiated rhabdomyosarcoma with HE staining often can not determine its tissue origin, and it is difficult to diagnose surgical pathology. Because myoglobin is only present in striated muscle, antibodies against myoglobin are a good marker for striated muscle tumors.