众所周知,在有遗传倾向的人群中,环境因素对解除胰腺β-细胞抗原的耐受性和促使自身免疫性(Ⅰ型)糖尿病的发病起着一定的作用。但是,这些抗原的本质仍有争论,它是病毒性还是饮食性的一直难下结论。现今,Karjalainin等提出一个令人感兴趣的假说,他认为产生胰岛素β-细胞的损害是由对牛奶的免疫应答所引起的。 It is well-known that environmental factors play a role in the release of pancreatic β-cell antigen and in the development of autoimmune (type 1) diabetes in people with genetic predisposition. However, the nature of these antigens is still debated, and it has been difficult to conclude whether it is viral or dietary. Nowadays, Karjalainin et al. Put forward an interesting hypothesis that he thinks the damage caused by insulin-producing β-cells is caused by the immune response to milk.