胰岛素瘤为胰岛β细胞肿瘤,占胰岛细胞肿瘤的70～75%,近年来我国文献报告逐渐增多,国外文献关于胰岛素瘤的诊治亦略有进展,兹归纳于下,以飨读者。胰岛素瘤的诊断症状学首先是诊断的依据,胰岛素瘤因分泌过多的胰岛素导致低血糖症,临床主要表现为脑组织缺乏葡萄糖引起的症状如神志迷糊、昏睡、昏迷、颠痫发作等。另一类症状为由低血糖诱发的儿茶酚胺释放所致的症状如出汗、心慌、苍白、脉速等。Whipple三联征仍有重要性,但不是每个病人均有典型发作。采用饥饿试验,据我院经验,90%的病例可以 Insulinomas are pancreatic islet β-cell neoplasms, accounting for 70-75% of islet cell tumors. In recent years, the number of reports in our country has gradually increased. The foreign literature on the treatment of insulinomas has also made slight progress, and is summarized as follows. Diagnosis of insulinoma symptoms is the basis for diagnosis, insulinoma due to excessive secretion of insulin leading to hypoglycemia, the main clinical manifestations of brain tissue lack of glucose-induced symptoms such as confusion, drowsiness, coma, seizures and so on. The other type of symptoms are symptoms caused by hypoglycemia-induced release of catecholamines such as sweating, palpitation, paleness, and pulse speed. The Whipple Triad is still important, but not every patient has a typical attack. Using the hunger test, according to the experience of our hospital, 90% of cases can