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目的评价金因肽在头颈部肿瘤患者放射治疗中的临床作用。方法将52例头颈部肿瘤放射治疗患者随机分为治疗组和对照组,每组各26例。治疗组患者给予放射治疗+漱口液+金因肽口腔喷雾,对照组患者为放射治疗+漱口液。结果急性口腔黏膜炎反应程度在放射治疗第5周、7周末时差异有统计学意义;在放射治疗结束时,两组患者贫血及体重下降>2.5 kg的患者比例差异有统计学意义。结论在头颈部肿瘤患者放射治疗时使用金因肽口腔喷雾,不仅可以降低急性口腔黏膜炎的发生率及反应级别,而且可以间接降低贫血发生及维持患者的体重,有利于放射治疗顺利进行及保证疗效。
Objective To evaluate the clinical effect of Jinyin Peptide in radiotherapy of head and neck cancer patients. Methods 52 patients with head and neck tumor radiotherapy were randomly divided into treatment group and control group, 26 cases in each group. Patients in the treatment group received radiotherapy + mouthwash + gold agent peptide spray, and patients in the control group received radiation therapy + mouthwash. Results The response degree of acute oral mucositis was statistically significant at the 5th and 7th weekend of radiotherapy. At the end of radiotherapy, the proportion of patients with anemia and weight loss >2.5 kg was significantly different between the two groups. Conclusion The use of golden peptide oral spray during radiotherapy of head and neck cancer patients not only can reduce the incidence and reaction level of acute oral mucositis, but also can indirectly reduce the incidence of anemia and maintain the weight of patients, which is conducive to the smooth progress of radiotherapy and Ensure efficacy.