1-Methyl-4-phenyl-1相关论文
The Influence of Substantia Nigra Neurons and Akt through Acupuncture of Chorea-tremble Controlled A
Objective To study the protective effect of acupuncture of Chorea-tremble controlled area combined with madopar on the d......
Paraquat and MPTP induce alterations in the expression profiles of long noncoding RNAs in the substa
Parkinsons disease (PD) is a common age-related degenerative disease of the central nervous system caused by hereditary,......
OBJECTIVE: To investigate whether scorpion extract elicits a neuroprotective effect in 1-methyl-4-phenyl-1,2,3,6-tetrahy......
目的 比较1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)所致的急性、亚急性和慢性帕金森病(PD)模型小鼠空间参考记忆和脑内多巴胺(DA)水......
Differential protein expression in substantia nigra induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahyd
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目的研究1-甲基-4-苯基-1，2，3，6-四氢吡啶(MPTP)所致急性帕金森病(PD)小鼠模型的焦虑行为。方法选取20只C57BL/6J小鼠，随机分为对照组(......
目的建立食蟹猴1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)帕金森病系统性模型,探讨嗅球中多巴胺(DA)及多巴胺/cAMP调节磷蛋白(DARPP32......
OBJECTIVE:To investigate whether scorpion ex-tract elicits a neuroprotective effect in 1-meth-yl-4-phenyl-1,2,3,6-tetrah......
Differential protein expression in substantia nigra induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahyd
BACKGROUND: To date, a complete protein expression profile of the midbrain substantia nigra in a mouse model of chronic ......
Study of apoptosis pattern of dopaminergic neurons and neuroprotective effect of nicotine in MPTP mo
Objective:To investigate the apoptosis of dopaminergic neurons and the protective effect of nicotine in 1-methyl-4-pheny......
Intrastriatal glial cell line-derived neurotrophic factors for protecting dopaminergic neurons in th
BACKGROUND: Substantia nigra is deep in position and limited in range, the glial cell line-derived neurotrophic factor (......
Establishing motor disorder mouse models of Parkinson disease Comparison of 6-hydroxydompamine and 1
BACKGROUND: At present, pathogenesis and mechanism of Parkinson disease (PD) are still unclear.Animal models of PD are e......
目的：观察神经生长因子（nerve growth factors，NGF）鼻腔给药对于t—methyl-4．phenyl-1，2，3，6-tetrahydropyridine（MPTP）所致的帕金森病模型小......
,Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-te
AIM: To observe the neuroprotective mechanism of modafinil on Parkinson disease (PD) models induced by 1-methyl-4-phenyl......
Study of apoptosis pattern of dopaminergic neurons and neuroprotective effect of nicotine in MPTP mo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
The present study observed the action of 1H-indole-2, 3-dione (isatin) on Bax protein expression in the substantia nigra......
目的观察1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)对小鼠学习和记忆行为的影响.方法 C57BL/6小鼠皮下注射8d MPTP(20mg/kg).测定小鼠......
[摘要]目的探讨A型钾通道抑制剂4-氨基吡啶（4-AP）对l-甲基4苯基-1，2，3，6-四氢吡啶（MPTP）诱导的帕金森病（PD）模型小鼠运动行为的影响。 方......
本文报道给C57小鼠腹腔注射不同剂量1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)后,发现组3(MPTP35 mg/kg,每天一次,共7天)鼠肝匀浆、线......
近年来有研究认为帕金森病（Parkinson’s Disease，PD）的高发病率可能与杀虫剂的广泛使用，即环境因素有关，而杀虫剂内含具有致多巴胺神经......
目的探讨针刺百会和大椎穴对帕金森病（PD）小鼠多巴胺能神经元的保护作用及可能机制。方法C57BL/6雄性小鼠随机分为5组：正常组、模型组......
目的探讨MPTP(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,甲基-苯基四氢吡啶)对小鼠下丘脑和海马内前炎症细胞因子IL-1β和IL......
目的：观察慢性长期小剂量注射1-甲基-4-苯基-1,2,3,6-四氢吡啶（1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPTP）对小鼠黑质多巴......
为了观察1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)对C57BL/6小鼠空间学习记忆能力和脑内强啡肽(DYN)表达强度的影响,本研究给予小鼠......
MADOPAR-INDUCED DYSKINESIA IN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) HEMIPARKINSONIAN M
Infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) into the right common carotid artery produced hemiparkin......
THE EFFECTS OF DEPRENYL AND 1-METHYL-4-PHENYL-1, 2, 3, 6-TETRAHYDROPYRIDINE (MPTP) ON 2-DEOXYGLUCOSE
~3H-2-deoxyglucose (2-DG) autoradiographic technique was used to study the ef feets of a monoamine-oxidase-B (MAO-B) inh......
本研究的目的是探讨蝎毒耐热蛋白（SVHRP）对1-甲基4-苯基-1，2，3，6-四氢吡啶（MPTP）处理的伴有空间学习记忆障碍的Parkinson病（PD）小鼠的保护机......
目的探讨姜黄素对C57BL／6小鼠帕金森病模型行为学的影响及常用行为学测试的比较。方法取30只C57BL／6雄性小鼠随机分成3组：MPTP模型组......
目的 探讨“抗帕颗粒”对1-甲基-4-苯基-1，2，3，6-四氢吡啶（MPTP）帕金森病（PD）模型小鼠黑质纹状体区α-突触共核蛋白（α-syn）异常聚集的影响......
拟建立一种不仅操作简便而且能较好模拟帕金森病（Parkinson＇s disease,PD）临床症状和病理进程的造模方法.选取健康老龄雌性恒河猴12只......
目的探讨1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）对不同年龄快速老化小鼠（SAMP8）急性损伤后黑质纹状体系统多巴胺（DA）含量及环氧化酶2（COX-......
OBJECTIVE To observe effects of tetrahydroxystilbene glucoside(TSG)on behavior,content of dopamine and its metabolites i......
目的：探讨1-甲基-4-苯基-四氢吡啶离子（1-methyl-4-phenyl-1，2，3，6-tetrahydropyr训ne，MPP^＋）诱导小鼠胚胎中脑原代培养多巴胺能神经元损伤......
目的：探讨1-甲基-4-苯基-四氢吡啶离子（MPP^＋）对小鼠胚胎中脑原代培养多巴胺能神经元的毒性作用及其机制。在体外建立帕金森病（PD）实验研......
Prenatal and Postnatal Exposures to 1-Methyl-4-phenyl-1,2,3,6-tetra Hydropyridine (MPTP) Impaired Mo
Dopamine cell bodies in the substantia nigra of the midbrain and with their terminals projecting to the neostriatum form......
目的：进一步探讨蝎毒耐热蛋白（SVHRP）改善MPTP（1-methyl-4-phenyl-1，2，3，6-tetrahydropyridine，MPTP）小鼠伴有空间学习记忆障碍的机制。方法......
目的:探讨甲基-苯基-四氢吡啶(MPTP)是否可诱导小鼠大脑皮质内细胞因子水平变化.方法:28只C57BL/6J雄性小鼠接受MPTP25mg/kgip注射......
Scorpion venom heat-resistant protein decreases immunoreactivity of OX-42-positive microglia cells i
BACKGROUND:Microglia function as the immune surveyors of the brain under normal physiological conditions.However,microgl......
