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目的:研究去甲肾上腺素(NE)介导大鼠肠系膜血管床(MVB)收缩的α1肾上腺素受体(α1AR)亚型.方法:用灌流大鼠MVB标本收缩功能实验和克隆细胞放射配体结......
Muscarinic stimulation rescues β_1-adrenergic response in transgenic mouse heart overexpressing β_2-
Cardiac specific overexpression of human β 2 adrenergic receptor (β 2 AR) in transgenic mice (TG4) enhances the b......
Objective:To investigatethecorrelationbetweenβ 2 -adrenergicreceptors(β 2 -AR)haplotypesandasthmaof Hannat......
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Chronic blocking of β3-adrenoceptor ameliorates cardiac function in rat model of heart failure funct
Background Stimulation of the heart β3-adrenoceptor(AR)may result in a negative inotropic effect.Being up-regulated,β3......
目的 检测一批新合成的α1-肾上腺素受体(α1-AR)拮抗剂对α1-AR的选择性拮抗活性.方法 ①通过吲哚哌啶与哌嗪分子耦合衍生,得到一......
单脉冲电场刺激大鼠输精管的附睾段主要引起肾上腺素能受体反应,动物预先经利血平化,肾上腺素能α-受体激动剂增强单脉冲刺激反应呈明......
为了揭示不同类型运动心脏交感神经的反应性及其调节机制,对经过跑台耐力训练与爬杆静力训练的实验大鼠心脏交感神经递质含量与肾......
Regulation ofβ2-adrenoceptors in brain glia:implications for neuroinflammatory and degenerative diso
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采用灌胃和静脉注射2种给药途径,观察给药1次14 d内小鼠的急性毒性反应;应用人参皂苷C-K(100 mg/kg)复制小鼠肺水肿模型,观察肾上腺......
摘要:β3-肾上腺素受体(β3AR)主要存在于具有产热功能的棕色和白色脂肪细胞上,β3AR激动剂可调节人体内热量平衡、葡萄糖代谢、能量......
以放射免疫分析法和放射配基结合分析法观察了人参对衰老大鼠β受体-cAMP系统的影响.结果表明衰老太鼠血浆cAMP基础值、反应性明显......
当绵羊心浦肯野纤维α-和β-受体分别激动时,用双微电极法电压箝制术研究慢内向离子流Isi和延迟整流外向离子流Ix的变化。心得安阻......
采用放射配体结合方法观察外源性氧自由基对大鼠心肌α_1肾上腺素受体(α_1受体)及其亚型α_(1A)与α_(1B)的影响和对β肾上腺素受体(β受体)的影......
Reducing sympathetic nervous tone in aged rats bettered cardiomyocyte contraction by improving the r
【正】The study was to investigate the effect of reducing central sympathetic nervous tone with clonidine on cardiomyocy......
目的:观察静脉注射α-肾上腺素能受体激动剂和拮抗剂以刺激交感神经(sympathetic stimulation,SS)对糖尿病痛过敏大鼠神经中C和Aδ单......
目的:研究α1肾上腺素受体拮抗剂哌唑嗪对脂多糖(LPS)诱导的大鼠血清中磷脂酶A2活性及肝细胞内钙离子浓度〔Ca2+〕i超载的抑制及其对......
简述肾上腺素受体的分型、功能及两种新的肾上腺素受体亚型.阐述选择性作用于肾上腺素受体药物的开发及其临床应用情况,详细介绍了......
目的检测一批新合成的α1-肾上腺素受体(α1-AR)拮抗剂对α1-AR的选择性拮抗活性。方法①通过吲哚哌啶与哌嗪分子耦合衍生,得到一系......
The effect of nebivolol on the production of nitric oxide induced by bacterial lipopolysaccharide an
Nitric oxide (NO) plays a pivotal role in main- taining balance of physiological events in many systems including the au......
目的:研究β1肾上腺素受体抗体在扩张性心肌病发病中可能的作用。方法:将14只新西兰兔随机分为两组,免疫组和对照组。β1受体肽段作为抗原......