DNA-Binding相关论文
The electronic structures, DNA-binding, SAR andspectral properties of ruthenium methylimidazole comp
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The development of promising photodynamic therapy(PDT) agents that bind to DNA for cancer treatment have drawn much more......
Synthesis,antibacterial activity and DNA-binding affinity of novel hybrid peptides from TAT(47-57)an
Breast cancer susceptibility gene(BRCA1)has been a focus of cancer research since its discovery in 1994[1].Cancer patien......
A cationic porphyrin-anthraquinone hybrid and its Zn(Ⅱ), Cu(Ⅱ), Co(Ⅲ), and Mn(Ⅲ) complexes were synthesized and thei......
A new dinuclear complex, [Ag(L)(CH3CN)]2(ClO4)2·2H2O(L=2,3-di-2-pyridylquinoxaline), was prepared and characterized by ......
作为对环磷酰胺结构改造新思路的延续,本文以化合物9i为先导物设计并合成了三个系列环磷酰胺哌嗪季铵盐类衍生物(10,11和13).通过......
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Electronic Structures, DNA-binding, SAR, and Spectral Properties of Ruthenium Methylimidazole Comple
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该文利用Gaussian98量子化学程序包,运用用密度泛函法(DFT),在B3LYP/LANL2DZ水平上,对[M(phen)]=Os(Ⅱ),Ru(Ⅱ),Co(Ⅲ)or Zn(Ⅱ);n......
Synthesis, structure, DNA binding and cleavage activity of a new copper(Ⅱ) complex of bispyridylpyrr
A copper-bispyridylpyrrolide complex [Cu(PDPH)Cl] (PDPH = 2,5-bis(2′-pyridyl)pyrrole) was synthesized and characterized......
Synthesis, Crystal Structure, Luminescent Property and DNA-Binding of a Cadmium Complex with 2,4-Bis
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Synthesis, Crystal Structure and Biological Properties of One Zinc(Ⅱ) Complex Based on 4-Acyl Pyrazo
本文通过对荣华二采区10...
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为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
用密度泛函理论,对钌多吡啶配合物1-3的DNA键合及光谱性质进行理论研究.首先,用密度泛函和分子对接方法,获得了配合物1-3和DNA对接......
目的 探讨叉头框蛋白Q1(FOXQ1)与结直肠肿瘤的临床病理相关性.方法 连续收集云南省第一人民医院2007年6月至2009年6月174份研究样......
C-repeat binding proteins (CBFs) are a group of transcription factors that have been proven to be important for stress t......
目的:构建人核糖体蛋白RPS3及其Ser209突变体的真核表达载体,初步探讨RPS3Ser209突变体对NF-κB转录活性及其DNA结合能力的影响。方法......
Binding of cordycepin to the double helical DNA with a high affinity was investigated by CD spectra in this paper. The r......
合成并表征了三个钌(Ⅱ)多吡啶配合物[Ru(phen)2(7-CH3-dppz)]^2+(i)、[Ru(phen)2(7-F-dppz)]^2+(ii)和[Ru(phen)2(7+CF3+dppz)]2+(iii).利用光谱法和粘度实验......
通过紫外光谱和荧光光谱法研究了三元铜配合物Cu(ODA)(NBZIM)(H_2O)(ODA=一缩二乙醇酸,NBZIM=6-硝基苯并咪唑)与小牛胸腺DNA(CT-DNA)之间的相......
目的:研究八聚精氨酸(Arg8)对一种新的人体蛋白结构域(Circadian locomoter output cycles kaput protein's DNA-binding pept......
An unsymmetrical oxovanadium complex [VO(SAA)(phen) ](1),(SAA = salicylidene anthranilic acid,phen = phenanthroline) and......
合成了由N-芳环、氮杂环和脂肪烃取代的5种吡啶酰胺类化合物:N-苯基-吡啶-2-甲酰胺(L1),N-2-氯苯基-吡啶-2-甲酰胺(L2),N-2-硝基苯基-吡啶......
合成并表征了2'6-二(苯并咪唑-2')吡啶(H2bzimpy)和铕(Ⅲ)的配合物,用电子吸收光谱、荧光光谱和粘度测定研究了配合物与DN......
合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Ni(L)(HL)](SO4)0.5·3CH3OH(1)和[Cu2(L)2SO4]·1.5CH3OH(2)的结......
文章合成了新的诺氟沙星-钇配合物,并应用荧光、黏度和热变性等方法,对此化合物与小牛胸腺DNA作用方式进行了研究。结果表明:配合物......
Small molecule compounds targeting DNA binding domain of STAT3 for inhibition of tumor growth and me
Background Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in malignant tumors and ......
hASH4蛋白所属的HLH转录因子家族在调节基因表达,调控细胞周期,决定细胞分化中起了重要作用。有研究表明hASH4蛋白可能与皮肤的分化......
The Dof (DNA-binding with one finger) proteins are a class of plant-specific transcription factors that can trigger seve......
本文合成了三种铂(Ⅱ)配合物PtLCl(HL1=2-(3′,5′-二甲基-吡唑-1′-基)-N-(2″-吡啶甲基)乙基胺;HL2=2-(3′,5′-二甲基-吡唑-1′-基)-N-(2″-......
合成并通过单晶衍射、元素分析及红外光谱表征了配合物[Ni(L)(OAc)](1)和[Co(L)2]Cl·4CH3OH(2)的结构(HL为2-乙酰-3-甲基吡嗪......
用密度泛函理论,在B3LYP/LanL2DZ水平上,对系列钌多吡啶配合物的电子结构和DNA键合倾向进行研究,分析这些配合物的电子结构性质,合理地......
用密度泛函理论,对钌多吡啶配合物1-3的DNA键合及光谱性质进行理论研究。首先,用密度泛函和分子对接方法,获得了配合物1-3和DNA对接的......
概述了紫外光谱法在研究金属配合物与DNA相互作用中的应用。紫外光谱法是一种研究配合物与DNA相互作用最简便、常用而有效的方法,......
以手性苯乙胺与吡啶醛缩合得到的含双齿或三齿配位基的手性席夫碱(L1、L2)为配体,合成了4对单核铁、镍手性对映体配合物fac-∧-[M(R—L......
合成了一个三羟基咔咯10-(4-羟基苯基)-5,15-双(4-(2-羟乙基)氨基-2,3,5,6-四氟苯基)咔咯(1)及其镓配合物(1-Ga)。光谱滴定实验、......
Two silver(I)-sulfonate complexes,[Ag(NO3)(4,4’-bipy)][Ag(HL)(4,4’-bipy)]·2H2O(1) and[Ag(H2O)(4,4’-bipy)][AgL(4,4’-bipy)]·2H......
目的采用凝胶迁移阻滞法分析研究人类端粒酶DNA结合特性.方法以地高辛标记的人端粒序列寡核苷酸与人端粒酶提取物进行结合反应,以......
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应用电子吸收光谱、荧光光谱和粘度测定等方法研究钌多吡啶配合物[Ru(phen)2(Hecip)]2(phen=1,10-邻菲啰啉,Hecip=2(9-乙基-9H-咔唑-3-基......
Photocleavage Properties and DNA-Binding Studies of Oxovanadium Complexes Incorporating 2-(2-Hydroxy
Three mononuclear oxovanadium complexes [VO(Hbid)(CF3PIP)] (1) (Hbid=(E)-2-(2-hydroxybenzylideneamino) isoindoline-1,3-d......
本文研究人白细胞髓过氧化物酶(MPO)体外代谢芳胺类致癌物4-氨基联苯(4-ABP),在H2O2存在下,MPO代谢活化4-ABP生成二种可与DNA共价结合的代谢产物,高效液相色谱和质谱......
WRKY蛋白参与植物对生物或非生物胁迫反应和一些发育、代谢过程,在植物中组成一个转录因子大家族.从水稻cDNA文库中分离到一个新的......
采用密度泛函的方法,结合导体极化连续模型研究了水溶性二价钌.甲基咪唑类配合物[Ru(MeIm)4iip]^2+。(1)、[Ru(MeIm)4tip]^2+0+(2)和[Ru(MeIm)42nt......
Bacterial genomic DNA is highly organized into one or few compacted bodies known as nucleoid, which is composed of DNA, ......