FILAGGRIN相关论文
Atopic dermatitis is a chronic inflammatory skin disease characterized by the dysregulation of the epidermal barrier and......
Objective:Filaggrin(FLG)is a protein expressed in the epidermis and involved in the maintenance of the epidermal barrier......
T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processi
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皮肤在保护身体免受环境损伤和水分流失方面发挥着关键作用.角化套膜和天然保湿因子被认为是皮肤水合功能的主要调节剂,其中丝聚蛋......
目的构建人类中间丝聚合蛋白(filaggrin,FLG)基因慢病毒载体及观察慢病毒表达载体介导的RNA干扰RNAi对人HaCat细胞FLG表达的影响。......
目的 探讨丝聚合蛋白(Filagrin,FLG)基因的突变与特应性皮炎(Atopic dermatitis,AD)的相关性.方法 提取50例汉族AD患者及100例健康......
T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processi
Background: Atopic dermatitis (AD) is characterized by defective skin barrier and imbalance in T helper 1/T helper 2 (Th......
丝聚蛋白在表皮含量丰富,主要存在于表皮的最外层,对表皮的屏障功能起着重要的作用.近年的研究发现,寻常性鱼鳞病及特应性皮炎的发......
目的 探讨丝聚蛋白表达水平与斑秃患者特应性素质和疾病严重程度的关系.方法 分析37例斑秃患者的临床资料及实验室资料,取斑秃皮损......
食物过敏已经成为全球性公共卫生问题。皮肤屏障结构主要由表皮角质层与颗粒层紧密连接结构共同构成,其主要功能是防止水分丢失和......
数据与方法 1 臨床资料 先证者:男,12岁,广东东莞人,学生,患者出生后2个月发病,四肢伸侧皮肤干燥,覆盖鱼鳞状鳞屑,冬季加重,夏季减......
目的:检测汉族寻常型鱼鳞病(IV)丝聚合蛋白基因的突变。方法:提取65例Ⅳ患者及70例健康对照者的基因组DNA,采用MassARRA(r)分子量阵列技术......
近年来,在类风湿性关节炎(RA)患者中发现了多种新的自身抗体,特别是针对自身抗原瓜氨酸肽如聚丝蛋白和它的环状形式即环瓜氨酸肽(CCP)......
丝集蛋白是类风湿关节炎相关的自身抗体。利用乙醇沉淀、HiPrep16/10QXL凝胶结合高效液相色谱离子交换层析(HPLC)纯化人表皮丝集蛋白,......
Atopic dermatitis(AD)is a chronic inflammatory skin disorder which can precede asthma and allergic rhinitis in a disease......
The epidermis represents an essential barrier versus a broad range of exogenous stimuli. To form a functional epidermis,......
The Effects of a Hyaluronan Lotion with a Molecular Weight of around 50 - 110 kDa on the Aged Atroph
Background: Hyaluronic acids act upon keratinocytes via CD44 receptors and regulate proliferation and differentiation. S......
Filaggrin (FLG) plays an important role in the epidermal barrier function, which identified in patients with ichthyosis ......
Atopic eczema treatment now and in the future:Targeting the skin barrier and key immune mechanisms i
The skin facilitates a number of key roles but its functioning can be impaired by disease.Atopic eczema is a chronic inf......
目的:研究苯并芘(BaP)对永生化人角质形成细胞(HaCaT)中的Caspase—14和FilaggrintuRNA表达的影响,探讨其与BaP所致的细胞损伤的关系。方......
Filaggrin和Caspase-14主要分布于表皮。它们不仅在表皮细胞的分化及皮肤屏障中起着重要的作用,而且与许多皮肤疾病存在一定联系。......
目的:观察马齿苋提取物对湿疹大鼠皮肤的治疗效果,探讨单品马齿苋的药效以及促进湿疹病变部位修复的作用机理。方法:1.SD大鼠70只,按......