GDC-0449相关论文
Enhanced anti-tumor efficacy by co-delivery of GDC-0449 with size-tunable polymeric SN38 nanoparticl
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal human cancer with a poor prognosis and a 5-year survival rate......
Hedgehog plays an important role in a wide range of physiological and pathological conditions.Paracrine activation of He......
目的探讨Hedgehog(Hh)信号通路在肝细胞癌(hepatocellular carcinoma,HCC)细胞中的作用及其机制。方法选取2株HCC细胞系HepG2和Hep......
The Hedgehog(Hh)signalling pathway is essential for cellular proliferation and differentiation during embryonic developm......
Objective: To review and evaluate vismodegib, the first US Food and Drug Administration (FDA) approved treatment for loc......
研究背景:颅颌面形态的生长模式,是一个错综复杂的过程,它包括前期的间充质细胞的聚集、细胞的增殖与凋亡以及后期的分化和成骨。H......