HYDROXYLASE相关论文
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Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPT-Pi
The present study aimed to determine whether a polysaccharide obtained from Spirulina platensis shows protective effects......
Single Nucleotide Polymorphism of CYP3A4 Intron 2 and Its Influence on CYP3A4 mRNA Expression and Li
In adult liver, CYP3A4 plays an important role in the metabolism of a wide range of endogenous and exogenous compounds. ......
IntroductiontoVitaminD:Themolecularstructureofvi-taminD(seeFigure1)iscloselyalliedtothatofclassi-calsteroidhormones(e.g.......
EFFECT OF ROSIGLITAZONE AND METFORMIN ON CLOMIPHENE CITRATE RESISTANCE IN WOMEN WITH POLYCYSTIC OVAR
Objective To evaluate the impacts of rosiglitazone and metformin on ovarian response, hirsutism and insulin action in wo......
目的探讨新疆南疆地区维吾尔族苯丙酮尿症(phenylketonuria,PKU)患儿苯丙氨酸羟化酶(phenylalanine hydroxylase,PAH)基因第5外显......
目的:探讨肾上腺性性征异常的诊断、鉴别诊断和治疗,特别是分泌性激素的肾上腺肿瘤的良恶性鉴别诊断和各种先天性肾上腺增生疾病的......
AIM: To determine if expression of colonic tryptophan hydroxylase-2(TPH2), a surrogate marker of neuronal 5-hydroxytrypt......
AIM:To observe the effects of Kupffer cells on hepaticdrug metabolic enzymes.METHODS:Kunming mice were ip injected with......
先天性肾上腺皮质增生症(congenital adrenal hyperplasia,CAH)是一组常染色体隐性遗传疾病,由肾上腺皮质激素合成途径中酶的缺陷......
这儿讨论的隐性遗传,只限于常染色体隐性遗传。这种遗传方式是由常染色体上的基因决定的,所以两个性别有同等机会受到影响。还有,......
2007164 Diagnosis, treatment and long-term following up of 223 patients with hyperphenylalaninemia detected by neonatal......
苯丙酮尿症(phenylketnuria,PKU)是一种因苯丙氨酸羟化酶(phenylalanine hydroxylase,PAH)缺陷导致苯丙氨酸(phenylalanine,phe)代......
Effect of adenovirus-mediated brain derived neurotrophic factor in early retinal neuropathy of diabe
AIM:To observe effect of adenovirus-mediated brain derived neurotrophic factor in early retinal neuropathy of diabetes i......
Long-term modifications of blood pressure in normotensive and spontane-ously hypertensive rats by ge
Arachidonic acid cytochrome P-450 (CYP) hydroxylase 4A isoforms, including 4A1, 4A2, 4A3 and 4A8 in the rat kidney, cata......
Differential and Reciprocal Regulation between Hypoxia-inducible Factor-αSubunits and Their Prolyl H
Hypoxia-inducible factor (HIF)-α subunits (HIF-1α,HIF-2α and HIF-3α),which play a pivotalrole during the developmen......
目的:酪氨酸羟化酶(tyrosine hydroxylase,TH)是儿茶酚胺类递质合成的限速梅,儿茶酚胺类递质对胰腺内分泌细胞的功能具有重要的调......
Human phenylalanine hydroxylase (PAH) cDNA was applied as a hybridization probe to analyzing the following 8 restrictio......
AIM:To observe the expression of proline hydroxylase domain 2(PHD2) in the retina of diabetic rats and investigate the r......
Effects of frying oil and Houttuynia cordata thunb on xenobiotic-metabolizing enzyme system of roden
AIM: To evaluate the effects of frying oil and Houttuynia cordata Thunb (H. cordata), a vegetable traditionally consumed......
An improved glucose-DAB-nickel immunohistochemistry method and its application on protozoan Stylonyc
Using a modification of the very sensitive glucose-DAB-nickel(GDN)immunohistochemistry method,FOS(the expression protei......
AIM:Human cytochrome P-450 2E1(CYP2E1)takes part inthe biotransformation of ethanol,acetone,many small-molecule substra......
Divalent metal transporter 1 expression and iron deposition in the substantia nigra of a rat model o
Extensive iron deposition has been observed in the midbrain substantia nigra(SN) of Parkinson’s disease(PD) patients,bu......
An Eperimental Study on the Transplantation of Human Fetal Brain Cells into Monkey Models of Parkins
Unilateral administration of methly-phenyl-tetrahydropyridine(MPTP) into the common carotid artery
Unilateral adminis......
目的:研究许旺细胞(Schwann Cell,SC)能否促进离体多巴胺(Dopamine,DA)神经元存活和生长。方法:取生后2~3d Sprague Dawley(SD)大......
Summary: To observe the effects of heterograft of glomus cells of carotid body on hemiparkinsonian rat models, rats wit......
Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tet
AIM: To observe the neuroprotective mechanism of modafinil on Parkinson disease (PD) models induced by 1- methyl-4-pheny......
BACKGROUND: Previous researches suggested that expression level of calbindin D28K mRNA decreased in substantia nigra (SN......
Neuronal quantity and ultrastructure in extracorticospinal tract of newborn rabbits with cerebral pa
BACKGROUND: The liver enzyme system and blood brain barrier function of newborn rabbits are incomplete. High level of bi......
Neural stem cells (NSCs) are effective in treating Parkinsonian animals.1 Although cell transplan-tation is considered a......
Feasibility of establishing model of Parkinson disease by injecting 6-hydroxydopamine at different p
BACKGROUND: Previous researches found that animal models with Parkinson disease (PD) could be established by injecting 6......
Transplantation of primary cultured embryonic mesencephalic neural precursor cells for treating Park
BACKGROUND: Choosing proper donor cells is one of keys in experimental and clinical studies on cell replacement therapy ......
目的研究鱼藤酮所致的帕金森病大鼠的脑内α-突触核蛋白(α-synuclein, ASN)分布。方法 Wistar大鼠随机分成两组,分别给予鱼藤酮和......
Intrastriatal glial cell line-derived neurotrophic factors for protecting dopaminergic neurons in th
BACKGROUND:Substantia nigra is deep in position and limited in range,the glial cell line-derived neurotrophic factor(GDN......
Polymorphisms at cholesterol 7α-hydroxylase,apolipoproteins B and E and low density lipoprotein rece
AIM: To investigate the relationship between gallbladderstone disease (GSD) and single nucleotide polymorphismsof chole......
BACKGROUND: Primary dystonia is a heterogeneous disease, with a complex genetic basis. In previous studies, primary dyst......
Objective:To study the effects and mechanism of homocysteine(Hcy)on Parkinson’s disease(PD)induced by 6-hydroxydopamine......
Improvement of Parkinsonian behavior with co-grafts of Schwann cells and neural stem cells in the ra
BACKGROUND: Due to the lack of autograft transplant rejection, Schwann cells (SCs) can promote the proliferation of embr......
BACKGROUND:It has been reported that the conversion of neural stem cells into dopaminergic neurons in vitro can be incre......
Panax notoginseng saponins influence on transplantation of neural stem cell-derived dopaminergic neu
BACKGROUND: Dopaminergic neurons differentiated from neural stem cells have been successfully used in the treatment of r......
目的探讨单点双注法制备帕金森病(Parkison’s disease,PD)大鼠模型的可行性。方法分别以两点法和单点双注法注射6-羟基多巴胺(6-O......
BACKGROUND: Human amniotic epithelial cells (HAECs) can differentiate into neurons, astrocytes,and oligodendrocytes. Th......
Protective effect of bone marrow-derived mesenchymal stem cells on dopaminergic neurons against 1-me
BACKGROUND: To date, the use of bone marrow-derived mesenchymal stem cells (MSCs) for the treatment of Parkinson’s dise......
BACKGROUND:Severe injury to dopaminergic neuronal cell bodies and their axon terminals in the substantia nigra pars comp......
Establishment of a Parkinson’s disease model in rats via striatal one-site double injection Feasibil
BACKGROUND: To date, many 6-hydroxydopamine (6-OHDA)-lesioned rat models have been established by injecting 6-OHDA into ......
Total saponins of Panax ginseng effects on proliferation and differentiation of human embryonic neur
BACKGROUND:Total saponins of Panax ginseng(TSPG) exhibits neuroprotection against Parkinson’s disease in the substantia......
Parallel relationship between microglial activation and substantia nigra damage in a rotenone-induce
BACKGROUND:Inflammatory injury induced by microglial activation plays an important role in the occurrence and developmen......
