Heparan相关论文
肾小球系膜细胞和细胞外基质(extra-cellular matrix,ECM)是肾小球重要的结构和功能单位。肾小球基底膜是特殊的ECM,它主要由IV型......
Effects of Heparin on Transforming Growth Factor-β_1 and Extracellular Matrix Components in the Glom
The effects of heparin on the expression of transforming growth factor-β 1 (TGF-β 1) and two extracellular matri......
Dear Editor,Childhood Disintegrative Disorder(CDD),also known as Heller’s syndrome and disintegrative psychosis,is a ra......
The extracellular matrix is a diverse composition of glycoproteins and proteoglycans found in all cellular systems.The e......
Glycosaminoglycans(GAGs) play a significant role in various aspects of cell physiology.These are complex polymeric molec......
类肝素酶在细胞表面的表达和分泌对于肿瘤血管的生成和转移的重要作用已越来越受到人们的关注。众所周知,类肝素酶又称内β-葡萄......
Fibroblast growth factor-2 (FGF-2) is a member of a large family of proteins that bind heparin and heparan sulfate and m......
烧伤、严重创伤、出血性休克、肠梗阻或电离辐射伤等的缺氧和低灌流都造成肠粘膜损伤、增大通透性等肠功能障碍,导致肠细菌移位、......
Propolis modulates vitronectin,laminin,and heparan sulfate/heparin expression during experimental bu
Objective:This study was aimed at assessing the dynamics of vitronectin (VN), laminin (LN), and heparan sulfate/heparin ......
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
Currently, hepatitis B virus(HBV), upon attaching to human hepatocytes, is considered to interact first with heparan sul......
Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain,such as a heparan,dermatan,chon......
The Cre-loxP system was introduced in theproduction of recombinant AAV (rAAV). Defective adenovi-rus AdLC was used as th......
Clinicopathological significance of heparanase and basic fibroblast growth factor expression in huma
AIM: Human heparanase is an endo-D-glucuronidase that degrades heparan sulfate/heparin and has been implicated in a vari......
Objective: To explore the expression and significance of heparanase in non-small cell lung cancer (NSCLC) regarding prog......
Enzymatic remodeling of heparan sulfate:a therapeutic strategy for systemic and localized amyloidose
In 1854,Rudolf Virchow introduced the term“amyloid”to indicate white waxy deposits that stained positive for iodine an......
Effect of hydroxyurea and etoposide on transduction of human bone marrow mesenchymal stem and progen
AIM: To study the effect of hydroxyurea and etoposide on transduction of human marrow mesenchymal and progenitor stem c......
粘多糖代谢病(MPS I H)又称 Hurler 氏综合征,为较少见的常染色体隐性遗传病,具有软骨粘多糖与硫酸乙酰肝素(heparan sulfate)贮......
Heparan sulfate (HS) is ubiquitously expressed on the surfaces and in the extracellular matrix of virtually all cell typ......
Morphological properties and proliferation analysis of olfactory ensheathing cells seeded onto three
This study aimed to examine the differences in the morphological properties and proliferation of ol-factory ensheathing ......
Severe fever with thrombocytopenia syndrome virus(SFTSV) is a globe-shaped virus covered by a dense icosahedral array of......
恶性肿瘤的侵袭和转移是导致病人死亡的主要原因。目前研究认为肿瘤细胞实现侵袭转移,必须首先穿越由细胞外基质(extracellular ma......
Diabetic nephropathy(DN),a long term complication of diabetes,is the most common cause of end-stage renal disease,increa......
肿瘤的侵袭转移是导致肿瘤患者死亡的主要原因,寻找引发肿瘤细胞侵袭与转移的因素并进行有效阻断是治疗肿瘤的重要方法之一。肿瘤......
AIM:To clarify the association of glypican-3(GPC3)expression with Wnt and other growth signaling molecules in hepatocell......
BACKGROUND: The carcinogenesis of hepatocellular carcinoma(HCC) is a multi-factorial, multi-step and complex process. Ea......
Glypican(GPC)is a family of heparan sulfate proteoglycans bounded to the cell surface through a lipid glycosyl-phosphati......
Characterization of a new monoclonal anti-glypican-3 antibody specific to the hepatocellular carcino
AIM To characterize the antigen on HepG2 cell that is specifically recognized by a new monoclonal antibody raised agains......
Inhibition of BACE1, the β-secretase implicated in Alzheimer’s disease, by a chondroitin sulfate ext
The pharmaceutical and anticoagulant agent heparin,a member of the glycosaminoglycan family of carbohydrates,has previou......
目的：检测脑胶质瘤组织中乙酰肝素酶和syndecan-1的表达水平,探讨它们和肿瘤级别的关系及作用机制。方法：采用荧光实时定量聚合酶链......
Currently, hepatitis B virus(HBV), upon attaching to human hepatocytes, is considered to interact first with heparan sul......
Proteoglycans are a group of molecules that contain atleast one glycosaminoglycan chain, such as a heparan,dermatan, cho......
许多哺乳动物的疱疹病毒利用一半作为受体在房间表面 proteoglycans 上介绍的 heparan 硫酸盐(HS ) 因为房间入口，和这个过程也要求......
磷脂酰肌醇聚糖-3蛋白（Glypican-3,GPC3,也称为DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS和SGBS1）是硫酸乙酰肝素糖蛋白（heparan sulfate......
目的：探讨乙酰肝素酶在宫颈黏膜上皮内瘤变（CIN）与宫颈鳞癌中的表达。方法：应用免疫组化SP法检测乙酰肝素酶在56例CIN（CINⅠ12例，CINⅡ26......
目的探讨RNA干扰沉默乙酰肝素酶基因对卵巢癌微血管内皮细胞的影响。方法实验组为乙酰肝素酶siRNA转染组（转染组），实验对照为正常组和......
Enzymatic remodeling of heparan sulfate：a therapeutic strategy for systemic and localized amyloidose
<正>In 1854,Rudolf Virchow introduced the term"amyloid"to indicate white waxy deposits that stained positive for iodine ......
硫酸乙酰肝素类似物PI-88是一种有前景的肿瘤生长及转移抑制剂，可作为肝癌切除手术后的辅助治疗，通过抑制血管生长而产生抗肿瘤作用......
Objective:Thrombolytic therapy is an established modality in the management ofacute myocardial infarction(AMI).But early......
A large number of microbial pathogens bind to heparan sulphate on eukaryotic cell surfaces. Heparan Sulphate Binding Pro......
Collagen/heparan sulfate porous scaffolds loaded with neural stem cells improve neurological functio
One reason for the poor therapeutic effects of stem cell transplantation in traumatic brain injury is that exogenous neu......
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