NOCICEPTION相关论文
Cortical Representation of Pain and Touch: Evidence from Combined Functional Neuroimaging and Electr
Human functional MRI studies in acute and various chronic pain conditions have revolutionized how we view pain,and have ......
Accumulating evidence suggests that obesity is associated with chronic pain.However,whether obesity is associated with a......
Involvement of Rac1 signaling pathway in the development of acute inflammatory pain induced by bee v
Objective The Rho GTPase ras-related C3 botulinum toxin substrate 1(Rac1)is a subfamily member of the Rho GTPase family ......
Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability
Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals.Ion channels play a vital role......
Chronic pain caused by peripheral inflammation has always been the difficulty for clinical treatment.Currently developed......
Major aspects of neuronal function are regulated by Ca2+ including neurotransmitter release, excitability, developmental......
There is strong evidence that spinal 5-HT3 receptor plays a facilitatory role in various pain states.Electrophysiologica......
Ligustrazine inhibits high voltage-gated Ca2+ and TTX-resistant Na+ channels of primary sensory neur
Objective Ligustrazine, also named as tetramethylpyrazine, is a compound purified from Ligusticum chuanxiong hort and ha......
Anti-inflammatory, analgesic and antipyretic activity of methanolic Tecomaria capensis leaves extrac
Objective: To evaluate the analgesic, anti-inflammatory and antipyretic activity of methanolic Tecomaria capensis (T. ca......
Mesocorticolimbic dopaminergic(DA)neurons have been implicated in regulating nociception in chronic pain,yet the mechani......
疼痛是长期困扰人类的临床、心理与社会问题。近年来,随着疼痛的神经机制研究的进展,相关研究日益指向疼痛相关的心理学过程。疼痛......
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Cutaneous nociception is essential to prevent individuals from sustaining injuries.According to the conventional point o......
Involvement of group III metabotropic glutamate receptors in the modulation of spinal nociceptive si
BACKGROUND:Previous morphological studies have demonstrated that group III metabotropic glutamate receptors (mGluRs) are......
OBJECTIVE: Annona tomentosa R.E.Fr is a species not endemic to Brazil that belongs to the phytogeographic areas of the A......
脊髓下丘脑束在从脊髓向间脑和脑干的信息传递过程中起着重要作用.我们对脊髓下丘脑束是否参与了大鼠内脏痛信号传导过程的研究结......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Involvement of group III metabotropic glutamate receptors in the modulation of spinal nociceptive si
BACKGROUND:Previous morphological studies have demonstrated that group III metabotropic glutamate receptors (mGluRs) are......
手术截断小鼠尾末端可诱发长期性的痛觉过敏和吗啡镇痛效应变化.这种长期性的变化可能是由于中枢神经系统的神经可塑性变化引起的(......
Objective: To investigate the antinociceptive effects of Riluzole administered intraperitoneally in three hyperalgesia m......
Ligustrazine inhibits high voltage-gated Ca2+ and TTX-resistant Na+ channels of primary sensory neur
Objective Ligustrazine, also named as tetramethylpyrazine, is a compound purified from Ligusticum chuanxiong hort and ha......
伤害性感受是通过交感和运动神经来接受中枢神经系统的调控。最近推出的有关伤害性感受相关中枢核团的研究进展。表现在：运用能够表......
本研究用细胞外记录方法研究大鼠黑质多巴胺能神经元伤害性反应的特点。共记录了194个多巴胺能神经元。其中,大多数神经元(78％)可被......
目的通过观测不同手术刺激下指光电容积脉搏波（finger photoelectric plethysmography，FPPG）变化的情况，探讨运用FPPG进行围术期伤害性......
本文结合笔者的工作，综述了近年来关于丘脑中央下核（Ｓｍ）在痛觉感受与痛觉调制中作用的研究。结果表明，它可能主要与痛觉的情绪激动成分有......
腹外侧眶皮层（ventrolateral orbital cortex，VLO）是眶皮层的主要成分，它与导水管周围灰质（PAG）、丘脑和其它皮层之间有广泛的纤维联系。......
Chronic pancreatitis(CP)continues to be a clinical challenge.Persistent or recurrent abdominal pain is the most compelli......
脊髓背角感觉神经元不仅在感觉信息的传递和调节中起到重要作用,也是各种内源性和外源性药物的作用靶位.为了解静脉麻醉剂异丙酚是......
手术截断小鼠尾末端可诱发长期性的痛觉过敏和吗啡镇痛效应变化.这种长期性的变化可能是由于中枢神经系统的神经可塑性变化引起的(......
While the activation of primary somatosensory(SI) cortex during pain perception is consistently reported in functional i......
目的:分析红核的抗伤害作用和有关机制.方法:用玻璃微电极细胞外记录大鼠脊髓背角广动力型神经元(wide dynamic range, WDR)的单位......
目的：探索与痛觉预期特异相关的脑区,并研究预期作用对大鼠丘脑-皮层神经元伤害性反应的影响。方法：采用经典的声音-激光条件反射模......
磷脂酶Ａ<sub>２</sub>（ＰＬＡ<sub>２</sub>）与Ｇ蛋白β<sub>ｒ</sub>亚单位的作用据ＴＩＮＳＩＳ卷２期６４—６５页报道：早在１９８８年Ａｘｅｌｒｏｄ等提出Ｇ蛋白偶联受体能激活ＰＬＡ。，花生四稀酸（ＡＡ）及其......
磷脂酶Ａ<sub>２</sub>（ＰＬＡ<sub>２</sub>）与Ｇ蛋白β<sub>ｒ</sub>亚单位的作用据ＴＩＮＳＩＳ卷２期６４—６５页报道：早在１９８８年Ａｘｅｌｒｏｄ等提出Ｇ蛋白偶联受体能激活ＰＬＡ。，花生四稀酸（ＡＡ）及其......
P2Y受体是代谢性G-蛋白偶联受体,在哺乳动物已发现8种P2Y受体,它们多表达在外周神经末梢、脊髓背根神经节神经元和脊髓神经元等部......
目的探讨缝隙连接阻断剂甘珀酸(CBX)注入大鼠小脑延髓池后,对由福尔马林唇下注射所引发的伤害性行为,以及三叉神经尾侧亚核(Sp5C)......
Lignstrazine inhibits high voltage-gated Ca^2＋ and TTX-resistant Na^＋ channels of primary sensory ne
...
为探讨谷氨酸及其离子型受体是否参与牙髓伤害性信息的传递，预先向大鼠左侧脑室分别注射谷氨酸N-甲基-D-天门冬氨酸（NMDA）受体拮抗剂5......
通过应用识别大鼠阿片μ－受体Ｃ末端３０个氨基酸残基特异性位点的豚鼠抗体，我们对ＭＯＲ－受体样免疫反应物质在日本猴下位脑结构中的分布进行免疫......
Melanocortin-4 Receptor Expression in the Rostral Ventromedial Medulla Involved in Modulation of Noc
The rostral ventromedial medulla (RVM) is a prominent component of the descending modulatory system involved in the cont......
目的研究咪唑安定对大白鼠脊髓腰膨大部位广动力范围神经元(WDR neuron)对伤害性刺激反应的影响.方法在脊髓表面使用不同剂量的咪......
Anti-inflammatory,analgesic and antipyretic activity of methanolic Tecomaria capensis leaves extract
Objective:To evaluate the analgesic,anti-inflammatory and antipyretic activity of methanolic Tecomaria capensis(T.capens......
目的观察不同剂量舒芬太尼全麻诱导下气管插管时指光电容积脉搏波（FPPG）的变化。方法择期行甲状腺或乳腺手术患者120例，年龄20-60岁，随......
Pain receptors, nociceptors inputs to the spinal cord and supra spinal structures triggering a prolonged but reversible ......
A number of studies have demonstrated that sex differentially affects responses to stress and pain. In this study, sex-r......
A number of studies have demonstrated that sex differentially affects responses to stress and pain. In this study, sex-r......
Aim: Repeated microinjections of non-opioid an-algesics into the midbrain periaqueductal gray matter and rostral ventro-......
The nucleus accumbens(NAc)is a subcortical brain structure known primarily for its roles in pleasure,reward,and addictio......
OPIOIDS MODULATE NMDA－EVOKED RESPONSES OF NEURONS IN THE SUPERFICIAL AND THE DEEPER DORSAL HORN OF T
ＯＰＩＯＩＤＳＭＯＤＵＬＡＴＥＮＭＤＡ－ＥＶＯＫＥＤＲＥＳＰＯＮＳＥＳＯＦＮＥＵＲＯＮＳＩＮＴＨＥＳＵＰＥＲＦＩＣＩＡＬＡＮＤＴＨＥＤＥＥＰＥＲＤＯＲＳＡＬＨＯＲＮＯＦＴＨＥＭＥＤＵＬＬＡＫ．Ｍ．Ｚｈａｎｇ；ＷａｎｇＸｉａｏｍｉｎ；Ａ．Ｍ．Ｐｅｔｅｒ.........
