PKc相关论文
目的 探究酸枣仁汤通过P2X7受体介导对氯苯丙氨酸（PCPA）失眠大鼠模型前额叶CaMKⅡ、PKC、P38MAPK mRNA和蛋白表达。方法 腹腔注射PCP......
目的 观察背俞指针疗法对胃食管反流病（Gastroesophageal reflux disease,GERD）大鼠PLCDAG-PKC信号通路的影响。方法 将50只大鼠随机......
甲基汞环境污染已成为全球性问题,日益引起人们的密切关注。长期接触低剂量甲基汞所致脑发育损伤机制一直是各国学者研究的热点。......
小麦是人类的主要食物来源之一,中国是最大的小麦生产国。确保小麦的优质和产量,对人类的生存和发展和维护世界和平具有重要意义。......
目的:观察并探讨针康法对脑缺血大鼠运动功能和缺血区脑组织形态学的改善情况、缺血半暗带区脑组织中缝隙连接通讯的调节作用,为针......
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[目的]建立副猪嗜血杆菌感染猪单核细胞的体外模型,研究黄芩苷在副猪嗜血杆菌(Haemophilus parasuis,HPS)感染猪单核巨噬细胞后对......
目的 骨科植入物磨损产生金属颗粒(Co-28Cr-6Mo)损导致骨溶解和骨科植入物失败，但其分子机制还不清楚.CXC趋化因子受体4(CXCR4)已被......
Protein arginine methyltransferase 5(PRMT5)symmetrically methylates arginine residues of histones and non-histone protei......
Background Metal(Co-28Cr-6Mo)particles separated from implants by wear cause osteolysis and the failure of orthopedic im......
目的 在本研究中,我们采用PKC 泛抑制剂处理CML 耐药细胞株,观察耐药倍数的变化并阐述其相关分子机制。方法 构建PKC-α,PKC-β,PK......
目的 三阴性乳腺癌由于缺乏有效的治疗靶点而易于复发和发生远端转移，正在威胁着女性的生命安全。因此，迫切需要开发出针对三阴性乳......
目的：纤维粘连蛋白(Fn)可以被基质金属蛋白酶(MMP)分解为纤维粘连蛋白碎片(Fn-f)。将Fn-f注入正常的间盘内，间盘会出现退变样改变；将F......
Fungus Induces the Release of IL-8in Human Corneal Epithelial Cells,Via Dectin-1-mediated PKC Pathwa
AIM To identify whether Aspergillus fumigatus hyphae antigens induced the release of IL-8 in anti-fungal innate immunity......
The disturbance of hippocampal CaMKII/PKA/PKC phosphorylation in early experimental diabetes mellitu
Aim: To studyhowhippocampalserine/threonine kinases signaling changes inthe early phase of diabetic rats (both type 1 an......
Objective PGE2 is one of the most abundant prostanoids in mammalian tissues,but its effect on neuronal receptors has not......
目的 观察益气除痰方对LEWIS肺i癌小鼠肿瘤生长及细胞周期调控相关因子P16、 p21、 PKC、 c-myc的影响.方法 建立C57BL小鼠lewis肺......
Objective It has been shown that sigma-1 receptor modulated many biological function and play an important role in neuro......
Membrane depolarization increases membrane PtdIns(4,5)P2 level through PKC betaⅡ and PI4kinase mecha
Membrane phosphatidylinostol 4,5-bisphosphates (PtdIns(4,5)P2, PIP2) is fundamentally important for maintaining function......
Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumu
Chronic exposure to opiates impairs hippocampal long-term potentiation (LTP) and spatial memory, but the underlying mech......
Glucocorticoids are the primary hormones that respond to stress and protect organisms from dangerous situations.The gluc......
Glucocorticoids,inactive form cortisone and active form hydrocortisone,are important stress hormones,maintain organisms ......
Aim Fragile X mental retardation protein (FMRP) is an RNAbinding protein important for the control of translation and sy......
B7-H4 was over expressed in many cancers and was associated with clinical progression.Although B7-H4 are most discussed,......
HSP90 involves in the elevation of HERG potassium channel protein via activation of prolonged α1A-ad
Autonomic system stimulation during stress may alter cardiac action potential and therefore induce ventricular arrhythmi......
[目的]探讨神经痛维持期脊髓背角辣椒素受体(transient receptor potential vanilloid type1,TRPV1)的活化形式及低频电针的干预作......
目的：肾脏缺血再灌注损伤是缺血性急性肾功能衰竭的重要损伤环节，也是肾脏移植中影响移植肾早期功能恢复及长期存活的主要因素。肾脏......
Silica nanoparticles induce abnormal mitosis and apoptosis by balance and regulation of PKC mediated
Researches had shown that SiNPs could damage seminiferous epithelium and reduce the quantity and quality of sperms, but ......
The Activation Mode of Spinal Cord Dorsal Horn TRPV1 at Maintenanceof SNI-Induced Neuropathic Pain a
[Objective] To investigate the activation modes of spinal cord dorsal horn (SCDH)transient receptor potential vanilloid ......
Membrane depolarization increases membrane PtdIns(4,5)P2 level through PKC beta Ⅱ and PI4kinase mech
Membrane phosphatidylinostol 4,5-bisphosphates (PtdIns(4,5)P2, PIP2) is fundamentally important for maintaining function......
EFFECTS OF INTERLEUKIN-1 ON VASCULAR CALCIUM SENSITIVITY FOLLOWING ENDOTOXIC SHOCK IN RABBITS AND IT
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Lysosomes respond to environmental cues by controlling their own biogenesis,but the underlying mechanisms are poorly und......
目的 探讨精氨酸血管加压素(AVP)对缺氧血管平滑肌细胞(VSMC)中PKC-α、δ和ε亚型蛋白表达的调节作用及其可能机制.方法 取50只Wi......
Drug resistance is a huge challenge for scientists and medicine workers,which manifests both in human and animals....
Drug resistance is a huge challenge for scientists and medicine workers,which manifests both in human and animals....
肌醇磷脂代谢与V-mos癌基因转化细胞的相关性,迄今为止未见报导。本文用6m2细胞（Moloney鼠类肉瘤病毒（含V-mos）温度敏感突变株（MoMuSVt......
目的观察依那普利和中药复方对糖尿病大鼠肾小球丝裂原活化蛋白激酶 (MAPK) ,蛋白激酶Cα(PKCα) ,转化生长因子β1(TGFβ1)表达和......
目的探讨蛋白激酶C epsilon(protein kinase C epsilon,PKC-ε)及碱性调宁蛋白(h1 calponin,h1 CaP)在妊娠小鼠子宫平滑肌细胞中总......
目的:探讨子痫前期(PE)血清激活血管平滑肌细胞蛋白激酶C-α(PKC-α)及前胶原Ⅰ表达是否由磷脂酶C-γ1(PLC-γ1)信息分子介导。方......
目的:研究蛋白激酶C(PKC)在冠心病的发生、发展中的作用。方法:测定87例心绞痛(AP)患者、91例急性心肌梗死(AMI)患者、90例健康对......
目的:分析维格列汀干预2型糖尿病大鼠后,大鼠肾脏病理学、肾功能、血脂、PKC-η以及PKC-ζ治疗前后的变化特点。方法:将60只雄性SD......
目的 探讨胃癌ｐ３５ 、ＰＫＣ 及ＣＤ４４ Ｖ６ 联合表达与淋巴结转移的关系。方法 采用免疫组化ＳＡＢＣ 法检测８０ 例胃癌组织中ｐ５３ 、ＰＫＣ 及ＣＤ４４ Ｖ６ 的表达。结果 胃癌组织中......
目的：探讨口腔癌耐药细胞KBV200中，蛋白激酶C(protein kinase C，PKC)α亚型的cDNA序列与肿瘤多药耐药性(multidrug resistance，MDR)的......
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