H2S protects endothelium cell against Hcy-induced apoptosis and promotes cystathionine-γ-lyase expre

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户:mddh9666
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Aim: To investigate the role of the H2S effect in atherosclerosis (AS).Methods: The HUVECs were divided into the following groups: (1) the control group; (2) the DLHomocysteine(Hcy) 10, 20, 40, and 200 μmol/Lgroups; (3) the sodium hydrosulfide (NarHS) 10, 60, 120, 240, and 300 μmol/L groups; and (4) the Hcy-NaHS 10, 20, 40,and 200 μmol/L Hcy+300 μmol/L NarHS groups.Each of the groups was further divided into 24 h and 48 h subgroups.After being treated with various amounts of the above mentioned, the status of HUVECs proliferation were detected by CCK-8 assay.
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