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  5. Noble dendrobium polysaccharides attenuate learning and memory deficits induced by lipopolysaccharid

Noble dendrobium polysaccharides attenuate learning and memory deficits induced by lipopolysaccharid

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：wind2121
【摘 要】
：
Aim: To investigate the protective effects of noble dendrobium polysaccharides (NDP) on lipopolysaccharide (LPS)-induced learning and memory deficits in rats, and explore the possible mechanisms.Metho
【作 者】
：
Li-na WANG Qi-hai GONG Fei LI Jing-shan SHI 
【机 构】
：
Department of Pharmacology, and Key Lab of Basic Pharmacology of Guizhou, Zunyi Medical College, Zun
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
noble dendrobium polysaccharides lipopolysaccharide learning and memory APP GSK- 
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Aim: To investigate the protective effects of noble dendrobium polysaccharides (NDP) on lipopolysaccharide (LPS)-induced learning and memory deficits in rats, and explore the possible mechanisms.Methods: Rats were treated orally with NDP (40, 80, and 160 mg.kg-1·d-1) for 7 d followed injection of LPS 20 μg (2 pg/pL) into the lateral ventricle to induce learning and memory deficits.The abilities of spatial learning and memory were tested by Morris water maze.
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