Multiple Site-specifically One-Pot Synthesis of Two Proteins by Bio-orthogonal Flexizyme System

来源 :第十一届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户:studentOfJXUFE
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Acetylation of lysine is a reversible post-translational modifications(PTMs),which plays a key role in regulating gene expression and dynamic transitions in chromatin remodeling[1].
其他文献
Platinum-based anticancer drugs have been widely used to treat various malignancies.
Vasular pericytes,important mural cells that protect vascular integrity in healthy tissues,are often associated with tumor development in pathological conditions,but their functions in cancer invasion
Benzoxazinone derivatives are small molecules with antiplatelet aggregation and antiviral and anticancer properties.
In Type Ⅱ diabetes,initial peripheral insulin resistance often progresses to insulin deficiency caused by beta cell dedifferentiation and apoptosis.
Alzheimers disease(AD)is the most common neurodegenerative illness in the elderly.
近年来,由于人工光捕获系统在太阳能电池、光传感器以及光催化等方面的重要应用,越来越多的科研团队致力于这一系统的研究。人们发展了多种多样的分子骨架,希望实现高效的能量转移过程。
Spreading of agricultural sprays on plant surfaces is a significant task,since it decreases pesticide/herbicide usage and thereby reduce the risk of environmental pollution.
Pyroptosis is a form of regulated cell death in mammalian cells that is triggered by activation of various inflammasome complexes,leading to the activation of the proteolytic enzymes caspase-1 or casp
作为呼吸链的核心,线粒体复合物Ⅰ-Ⅳ依次催化一系列氧化还原反应,保证了电子和质子的有序传递,从而为能量的高效合成提供了基础。整个过程中,复合物之间是否存在协同作用,是否发生直接接触,是线粒体研究的一个焦点和难点。
The use of transition-metal complexes in medicine has enjoyed extensive attention given the tremendous success of cisplatin as a chemotherapeutic agent.