Severe adverse reactions of vitamin K1 injection are anaphylactoid reaction, not anaphylaxis

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户:senkooqian
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: Adverse reactions of vitamin K1 (VK1) injection are considered as anaphylaxis.The study is to clarify a hypothesis that it is an anaphylactoid reaction.Methods: Beagle dogs were administered intravenously to observe behavioral responses.Plasma histamine and IgE were assayed by ELISA.Blood pressure was recorded via biological functional system.
其他文献
Aim: Female-controlled topical microbicides for prevention of sexually transmitted diseases (STDs) are a diverse group of active ingredients that are capable of affecting microorganisms growth in vari
Aim: The dorsal raphe nucleus (DRN) is critically involved in sleep-wake regulation, but our understanding of the mechanisms of this regulation remains incomplete.The present study was designed to det
Aim: KCTD12 and KCTD16 were recently identified as GABAB receptor auxiliary subunits, yet their functional significance has yet to be clearly elucidated.Here we characterised the impact of human KCTD1
Aim: Hypoxic pulmonary vasoconstriction (HPV) can be modulated through either elevation of [Ca2+]i by Ca2+-dependent mechanism or inhibition of MLCP by Ca2+-independent mechanism.TRPC channels constit
Aim: To investigate the role of the H2S effect in atherosclerosis (AS).Methods: The HUVECs were divided into the following groups: (1) the control group; (2) the DLHomocysteine(Hcy) 10, 20, 40, and 20
Aim: Calcitonin gene-related peptide (CGRP) is a predominant neurotransmitter in sensory nerves.It has been reported that the expression of CGRP in lung was decreased in PF patients evoked by crystall
Aim: Bis-(2-ethylhexyl) phthalate (DEHP) is a manufactured chemical that makes plastic more flexible.Exposure to DEHP has recently been shown to possess a potential health hazard in premature infants
Aim: Referring to the relation between hypertension and long-term high-purine diet, we established the hypertension model mice by feeding with high-purine food, which is similar to human diseases.Meth
Aim: It has been shown that spinal D-amino acid oxidase (DAAO) might be a potential molecular target for the treatment of chronic pain and morphine tolerance to analgesia.This study evaluated the in v
Aim: The coordinated balance between osteoblastic bone formation and osteoclastic bone resorption is a kind of key target of anti-osteoporotic agents.Now among therapeutics currently used to treat ost