【摘 要】
：
Autophagy is an essential component of host innate and adaptive immunity.Viruses have developed diverse strategies for evading or utilizing autophagy for survival.The response of the autophagy pathway
【机 构】
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Key Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University, Hangzhou 310058,
【出 处】
：
The 1st NI-CMI Joint Conference(第一届CMI-NI免疫学国际研讨会)
论文部分内容阅读
Autophagy is an essential component of host innate and adaptive immunity.Viruses have developed diverse strategies for evading or utilizing autophagy for survival.The response of the autophagy pathways to virus invasion is poorly documented.Here, we report on the induction of autophagy initiated by the pathogen receptor heat shock protein 90 alpha (HSP90AA1) via the AKT-MTOR (mechanistic target of rapamycin)-dependent pathway.Transmission electron microscopy and confocal microscopy revealed that intracellular autolysosomes packaged avibimavirus particles.
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