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以小檗碱、黄芩甙、栀子甙为指标成分，对黄莲解毒颗粒剂用４种提取方法进行比较，结果３种成分总量顺序为：半仿生提取法＞半仿生提取醇法＞水提取法＞水提取醇沉法。
The berberine, radix astragali and medlar oxime were used as index components. The results were compared with the four extraction methods of Huanglian Jiedu granules. The results were as follows: Semi-bionic extraction method> Semi-bionic extraction alcohol method> Water Extraction method> Water extraction alcohol precipitation method.