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[目的]对2015年收集的广东省各肿瘤登记处上报的2012年恶性肿瘤登记资料进行分析,估计广东省恶性肿瘤的发病与死亡水平。[方法]全省共收到9个登记处上报的2012年肿瘤登记数据,通过审核和评估,共8个肿瘤登记处的数据符合入选标准。将入选的登记处按地区(城乡)、性别以及年龄别、肿瘤别发病率和死亡率分层,结合2012年全省人口数据,估计全省恶性肿瘤合计和主要肿瘤的发病、死亡情况。标化率采用全国2000年人口普查和世界Segi’s人口结构为标准。[结果 ]全省8个肿瘤登记处共覆盖登记人口15 084 942人,占全省总人口17.47%。病理诊断比例为72.84%,只有死亡证明书比例为0.87%,死亡/发病比为0.56。据估计,广东省2012年新发恶性肿瘤病例约21.1万例,死亡病例约11.7万例。全省恶性肿瘤发病率为250.20/10万(男性265.39/10万,女性234.29/10万),中国人口标准化发病率(中标率)为207.04/10万,世界人口标化率(世标率)为201.34/10万,累积率(0~74岁)为22.91%。城市地区发病率为267.25/10万,中标率为221.43/10万,农村地区发病率为215.51/10万,中标率为178.77/10万。全省恶性肿瘤死亡率为148.44/10万(男性190.95/10万,女性105.06/10万),中标率为103.73/10万,世标率为102.44/10万,累积率(0~74岁)为11.68%。城市地区死亡率为164.57/10万,中标率为105.46/10万,农村地区死亡率为124.63/10万,中标率99.97/10万。肺癌、肝癌、女性乳腺癌、结肠癌和鼻咽癌是广东省恶性肿瘤发病的前5位,肺癌、肝癌、结肠癌、胃癌和鼻咽癌是前5位的肿瘤死因。[结论]肺癌、肝癌、结肠癌、女性乳腺癌以及鼻咽癌的疾病负担沉重,是威胁居民健康的主要恶性肿瘤。在肿瘤防控工作中,针对不同癌种进行早预防,早期发现,早期治疗,提高生存质量,减轻疾病负担是我们面临的重要问题。
[Objective] To analyze the malignant tumor registration data of 2012 collected by Guangdong Provincial Tumor Registry in 2015 and estimate the incidence and mortality of malignant tumor in Guangdong Province. [Method] A total of 2012 cancer registration data reported by 9 registries was received in the province. Through the review and assessment, the data of 8 tumor registries met the inclusion criteria. The selected registries will be stratified by region (urban and rural areas), sex and age, morbidity and mortality of cancer, and the population of 2012 in the whole province will be used to estimate the total number of malignant tumors in the province and the incidence and mortality of major tumors. Standardization rate using the national 2000 population census and the world Segi’s population structure as the standard. [Results] There were 15 084 942 registered population in 8 tumor registries in the province, accounting for 17.47% of the total population of the province. Pathological diagnosis was 72.84%, only the death certificate was 0.87%, the death / illness ratio was 0.56. It is estimated that Guangdong Province in 2011 about 21.1 cases of new malignant tumor cases, about 117,000 deaths. The incidence of malignant tumors in the province was 250.20 / 100,000 (265.39 / lakh for men and 234.29 / lakh for females), and the standardized rate of population demise in China was 207.04 / lakh. The world population standardization rate (World standard rate) 201.34 / 100000, the cumulative rate (0-74 years) was 22.91%. The incidence rate in urban area was 267.25 / 100000, the successful rate was 221.43 / 100000, the incidence rate in rural areas was 215.51 / 100000, the successful rate was 178.77 / 100000. The province’s malignant tumor mortality rate was 148.44 / 100000 (male 190.95 / 100000, female 105.06 / 100000), the winning rate was 103.73 / 100000, the world standard rate was 102.44 / 100000, the cumulative rate (0-74 years old) 11.68%. The death rate in urban areas was 164.57 / 100000, the successful rate was 105.46 / 100000, the rural death rate was 124.63 / 100000, the winning rate was 99.97 / 100000. Lung cancer, liver cancer, female breast cancer, colon cancer and nasopharyngeal cancer are the top 5 malignant tumors in Guangdong Province. Lung cancer, liver cancer, colon cancer, gastric cancer and nasopharyngeal cancer are the top five tumor causes of death. [Conclusion] The disease burden of lung cancer, liver cancer, colon cancer, female breast cancer and nasopharyngeal carcinoma is heavy, which is a major malignant tumor threatening the health of residents. In the work of cancer prevention and control, it is an important issue that we face for early prevention, early detection, early treatment, improvement of quality of life and reduction of disease burden for different types of cancer.