在医院自制制剂中的酚甘油、复方硼砂溶液、复方薄荷学醑、复方炉甘石洗剂、樟脑酚液等制剂中,都含有苯酚。因为苯酚有较强的腐蚀性,所以一般都配制成液化苯酚,以易于使用。而液化苯酚的配制,目前一般大都采用水浴加热液化,此方法具有配制方法简单,配制时间短,易于操作等优点。但用此法配制的液化苯酚,通常颜色都较深;在夏季配制时,颜色更深,常显红棕色,有时甚至呈深棕色。这是因为苯酚易被氧化成有色的醌类,使溶液呈红色。在加热的条件下,苯酚更易被氧化。而我们用此法配制的液化苯酚,配制酚甘油滴耳液,有时也会因液化苯酚的颜色深,而呈深粉红色,含量也偏低,常需再添加一定量的苯酚,才符合质量要求。同时也增加了质量检测人员的工作量。 基于水浴法配制液化苯酚的不足,我们试用了 Phenol in the hospital preparation of glycerol, borax compound solution, compound mint study 醑, compound calamine lotion, phenol and other preparations of camphor phenolics, all contain phenol. Because of the strong corrosive phenol, it is generally formulated into liquefied phenol for ease of use. The preparation of liquefied phenol, the current general use of water bath heating liquefaction, this method has the preparation method is simple, preparation time is short, easy to operate and so on. However, the liquefied phenol prepared by this method is usually darker in color. When formulated in summer, the color is darker and often reddish brown, sometimes even dark brown. This is because phenol is easily oxidized to colored quinones, rendering the solution red. Under heated conditions, phenol is more susceptible to oxidation. And we use this method of liquefaction of phenol, the preparation of phenol glycerol ear drops, sometimes due to liquefied phenol color deep, but dark pink, low content, often need to add a certain amount of phenol, only in line with the quality Claim. At the same time, it also increases the workload of quality inspectors. Based on the lack of preparation of liquefied phenol water bath, we have tried