Prevalence and knowledge of hepatitis C in a middle-aged population,Dunedin,New Zealand

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:lovetianbing
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
AIM:To determine the prevalence of infection with hepatitis C virus(HCV) in those most at risk of advanced liver disease and to identify gaps in knowledge of HCV.METHODS: Questionnaires were mailed to randomly selected residents aged 40-59 to assess the extent of their general knowledge about HCV. The questionnaire assessed demographics, the extent of general knowledge about viral hepatitis, potential risks for infection and the prevalence of risk factors associated with increased progression of liver fibrosis. Anonymised residual laboratory blood samples from 40-59 years old people from Dunedin taken in hospital or in the community, were tested for HCV antibodies and alanine transaminase(ALT), aspartate transaminase(AST), gamma-glutamyl transpeptidase(GGT). Linear regression was performed to examine whether the demographics sex, age, socio-economic status, qualification level and occupation sector(categorical variables) were predictors of level of general knowledge about hepatitis. For the demographics that werefound to be significant predictors of score outcome, multiple regression analysis was used to determine independent effects. χ2 tests were used to compare our selected sample and our responder population demographics, to the demographics of the entire 40-59 years old population in Dunedin using the 2006 NZ census data. Exact confidence intervals for the proportion positive for HCV and HBV were calculated using the binomial distribution.RESULTS: The response rate to the mailed questionnaire was 431/1400(30.8%). On average 59.4% questions were answered correctly. Predictors for higher scores, indicating greater knowledge about symptoms and transmission included sex(female, P < 0.01), higher level of qualification(P < 0.000) and occupation sector(P < 0.000). Sharing intravenous drug utensils was a known risk factor for disease transmission(94.4%), but the sharing of common household items such as a toothbrush was not. 93% of the population were unaware that HCV infection can be asymptomatic. 25% did not know that treatment was available in New Zealand and of those who did know, only 40% assumed it was funded. Six hundred and eighty-two residual anonymised blood samples were tested for HCV antibodies, ALT, AST and GGT. The prevalence for HCV was 4.01%, 95%CI: 2.6%-5.8%. Liver function tests were not useful for identifying likelyhood of HCV infection.CONCLUSION: Prevalence of HCV in our population is high, and the majority have limited knowledge of HCV and its treatment. AIM: To determine the prevalence of infection with hepatitis C virus (HCV) in those most at risk of advanced liver disease and to identify gaps in knowledge of HCV.METHODS: Questionnaires were mailed to randomly selected aged 40-59 to assess the extent of their general knowledge of HCV. The questionnaire assessed demographics, the extent of general knowledge about viral hepatitis, potential risks for infection and the prevalence of risk factors associated with increased progression of liver fibrosis. Anonymised residual laboratory blood samples from 40-59 years old people from Dunedin in hospital or in the community, were tested for HCV antibodies and alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyl transpeptidase (GGT). Linear regression was performed to examine whether the demographics sex, age, socio-economic status, qualification level and occupation sector (categorical variables) were predictors of level of general knowledge about hepatitis. Fo χ2 tests were used to determine our selected sample and our responder population demographics, to the demographics of the entire 40-59 years old population in Dunedin using the 2006 NZ census data. Exact confidence intervals for the proportion positive for HCV and HBV were calculated using the binomial distribution .RESULTS: The response rate to the mailed questionnaire was 431/1400 (30.8%). On average 59.4% questions were answered correctly. Predictors for higher scores, indicating greater knowledge about symptoms and transmission included sex (female, P <0.01), higher level of qualification (P <0.000) and occupation sector (P <0.000). Sharing intravenous drug utensils was a known risk factor for disease transmission (94.4%), but the sharing of common household items such as a toothbrush was not. 93% of the population were unaware that HC Vinfection can be asymptomatic. 25% did not know that treatment was available in New Zealand and of those who did know, only 40% assume it was funded. Six hundred and eighty-two residual anonymous blood samples were tested for HCV antibodies, ALT, AST and GGT. The prevalence for HCV was 4.01%, 95% CI: 2.6% -5.8%. Liver function tests were not useful for identifying likelyhood of HCV infection.CONCLUSION: Prevalence of HCV in our population is high, and the majority have limited knowledge of HCV and its treatment.
其他文献
由中国空间科学学会空间遥感科学技术分会主持的“第二届全国地物光谱学术讨论会”,于1982年9月10日至15日在安徽绩溪举行。出席会议的有直接从事地物光谱科学研究的科研、
我厂自行设计和制造的两台油、气联动吹芯机,经一年多时间的使用证明,传动平稳、动作准确、运转正常。目前,国内一些工厂所生产和使用的吹芯机,均以气压传动为基本形式,而本
主持人语当下的中学作文教学,几乎与生活隔绝了,更无视学生的语文学习生活,已深深陷入瞄着高考作文的高度和要求、“教师仿真命题,学生应付枯写”这一恶性循环的泥潭之中,在
为了探讨列车在运行过程中噪声特点及其变化规律,为开展列车噪声防治和制定卫生标准提供科学依据,我们于1980年8月初对徐州至青岛的205/206次直快列车进行了初步凋查测定。
随着我国与世界的交流日益增多,外语知识的重要性逐步凸显。作为外语中常用语种之一,英语的应用范围相对较广。因此,加强英语教学的质量具有重要的现实意义。在初中英语教学
已经证实烧伤后免疫反应的显著改变与损伤程度有关,而且常被认为是引起严重烧伤患者创面脓毒症恶化而死亡的原因。然而,对这种免疫学改变的精确机理,是免疫缺陷还是免疫抑制
文化视野下的物理教学通常应当以文化为根本,通过拓展视野等形式能够使已经凝固的文化重新活跃,使学生能够在探究中学习物理知识,掌握科学的方法进行学习,体会物理学科的深层
耐火材料厂成型压砖机一般采用空气风动压把,操作上节省人力,但是噪声较大,压把排气筒噪声达118分贝。为了改善劳动条件,我厂制成一种简易风动压把消声器。 这种消声器是用厚
编辑同志:当前,我国对标准化工作极为重视,各行各业的标准化工作已成为促进四个现代化的措施之一。因此,我们在科技领域内所用的各种单位应一律采用国际单位制中规定的单位
吉林省光学学会于81年6月10日至13日在长春市召开了成立大会。来自五十多个单位的100名代表出席了会议。大会通过了吉林省光学学会章程,并选出以著名科学家王大珩为理事长的