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目的分析扬中市2004-2009年病毒性肝炎流行趋势,为探讨控制措施提供依据。方法回顾性调查2004-2009年扬中市病毒性肝炎疫情资料,通过发病率线形回归模型,估计病毒性肝炎发病率的年度变化百分比(APC)。结果 6年间扬中市病毒性肝炎中甲型、乙型和未分型肝炎发病率呈下降趋势(均有P<0.05),APC分别为-61.902%、-61.864%和-57.216%。病毒性肝炎以30～59岁为发病高峰年龄(60.77%),男、女性别比为2.75∶1,各型肝炎均以农民和工人发病为主(74.26%),存在季节和地区分布差异。结论在重点人群中开展甲肝、乙肝疫苗的接种、加强预防接种为主导的综合性防治措施是控制甲、乙型肝炎疫情发生与流行的有效方法,同时戊肝已成为扬中市重点预防控制传染病之一,应采取综合性防治措施。
Objective To analyze the epidemic trend of viral hepatitis in Yangzhong City from 2004 to 2009 and provide the basis for exploring control measures. Methods The data of epidemic situation of viral hepatitis in Yangzhong from 2004 to 2009 were retrospectively reviewed. The annual percentage change of incidence of viral hepatitis (APC) was estimated by linear regression model. Results The incidence of hepatitis A, B, and non-segregating hepatitis in Yangzhong was decreased in 6 years (all P <0.05). The APC were -61.902%, -61.864% and -57.216%, respectively. The peak age of onset of viral hepatitis was 30-59 years old (60.77%). The ratio of male to female was 2.75:1. The incidence of each type of hepatitis was mainly farmers and workers (74.26%). There were differences in seasonal distribution and regional distribution. Conclusion Hepatitis A and B vaccination among key populations and comprehensive vaccination-led prevention and control measures are effective methods to control the outbreak and epidemic situation of hepatitis A and B virus. At the same time, hepatitis E has become the focus of prevention and control of infectious diseases in Yangzhong One, should take comprehensive prevention and control measures.