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对56例手术治疗的急性阑尾炎进行了前瞻性的细菌学研究。结果提示引起阑尾炎的病原菌都是消化道内的正常菌群,且绝大部分为多菌性的混合感染,其中需氧菌以大肠杆菌等革兰氏阴性杆菌为主,而厌氧菌则以脆弱群拟杆菌多见,其次是各种消化链球菌。通过对全部需氧菌及部分厌氧菌作抗生素敏感试验,认为应以庆大霉素+甲硝唑为治疗急性阑尾炎的首选、常规药物。
A prospective, bacteriological study of 56 patients with surgical treatment of acute appendicitis was conducted. The results suggest that the pathogens causing appendicitis are normal flora in the digestive tract, and the vast majority of multi-bacterial mixed infection, of which aerobic bacteria Escherichia coli and other gram-negative bacilli, while the anaerobic bacteria are fragile Bacteroides Bacteroides more common, followed by a variety of Peptostreptococcus. Through all the aerobic bacteria and some anaerobic bacteria for antibiotic susceptibility testing, that gentamicin + metronidazole should be the first choice for the treatment of acute appendicitis, conventional drugs.