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Alzheimer病患者易患卒中的因素包括载脂蛋白E_4及脑淀粉样血管病。脑淀粉样血管病可呈现Alzheimer病的特点,其发病率达90%。文献已表明Alzheimer病与卒中有关,但其对脑血管病作用机理所知甚少。本文对145例Alzheimer病患者的尸体进行了解剖研究。 结果 轻度淀粉样血管病与重度淀粉样血管病相比,高血压、血清胆固醇水平、糖尿病、冠心病等的发病率均无显著差异。但重度淀粉样血管病脑梗塞
Factors that predispose to stroke in patients with Alzheimer’s disease include apolipoprotein E 4 and cerebral amyloid angiopathy. Cerebral amyloid angiopathy can present the characteristics of Alzheimer’s disease, the incidence rate of 90%. Literature has shown that Alzheimer’s disease and stroke, but its mechanism of action of cerebrovascular disease little understood. In this paper, we dissected the body of 145 Alzheimer’s patients. Results mild amyloid angiopathy compared with severe amyloid angiopathy, hypertension, serum cholesterol, diabetes, coronary heart disease incidence rates were not significantly different. However, severe amyloid angiopathy cerebral infarction