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乙型肝炎病毒(HBV)的感染是世界性的,我国属高度流行区(感染率为8～15％,慢性携带者有1亿人口,传染性很强的HBeAg携带者有3千万),认识乙型肝炎的感染过程及转归,对防治乙型肝炎(HB)极为重要。HBV的感染与其他病毒感染性疾病一样,可有不同类型的感染结局,由不显性感染到显性感染;由急性、暴发性感染到慢性持续感染,甚至长期无症状带毒状态。HBV慢性持续感染的严重性,不仅在于可导致肝硬化及肝癌,而且做为传染源,对易感人群将造成极大的威胁。本文从几个方面讨论HBV感染的转归,血清学变化及防治方法。
Hepatitis B virus (HBV) infection is worldwide, and our country is a highly endemic area (infection rate is 8 to 15%, chronic carriers have 100 million population, highly infectious HBeAg carriers have 30 million), Recognition of hepatitis B infection process and outcome, prevention and treatment of hepatitis B (HB) is extremely important. HBV infection, like other viral infections, can have different types of infections, from insignificant infection to dominant infection, from acute, fulminant infection to chronic persistent infection, or even long term asymptomatic infection. The severity of chronic persistent HBV infection is not only due to liver cirrhosis and liver cancer, but also as a source of infection, will pose a great threat to susceptible populations. This article discusses in several aspects of the outcome of HBV infection, serological changes and prevention methods.