糖尿病患者踝肱指数影响因素的研究

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目的:了解糖尿病患者踝肱指数的影响因素。方法:采用多普勒血流探测仪测定68例糖尿病患者的踝肱指数(Ankle-branchial index,ABI),ABI比值小于0.9为低ABI组,大于1.3为高ABI组,在0.9到1.3之间(含1.3)为正常组。结果:本组病例中ABI<0.9者11例,占16.18%,ABI>1.3者8例,占11.76%。低ABI组与正常组比较,前者年龄大、病程长,其脉压、HbA1C、TG、冠心病合并率、视网膜病变发生率明显增高。高ABI组与正常组比较,前者年龄大、病程长,其脉压、HbA1C、TG明显增高,HDL-C明显降低。多因素logistic逐步回归分析显示年龄、病程是导致ABI异常的危险因素。结论:多个因素影响糖尿病踝肱指数变化。 Objective: To understand the influencing factors of ankle brachial index in diabetic patients. Methods: The ankle-branchial index (ABI) of 68 diabetic patients was measured by Doppler flow detector. The ABI of ABI was less than 0.9 in ABI group, higher than 1.3 in ABI group, and 0.9 to 1.3 in ABI group (Including 1.3) for the normal group. Results: There were 11 cases with ABI <0.9 in this group (16.18%) and 8 cases (ABI> 1.3) accounting for 11.76%. Low ABI group compared with the normal group, the former older, longer duration, the pulse pressure, HbA1C, TG, coronary heart disease combined rate, the incidence of retinopathy was significantly higher. High ABI group compared with the normal group, the former older, longer duration, the pulse pressure, HbA1C, TG was significantly higher, HDL-C was significantly lower. Multivariate logistic regression analysis showed that age and course of disease were the risk factors for ABI abnormalities. Conclusion: Several factors affect the changes of diabetic ankle-brachial index.
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