biologic相关论文
Uncommon N-Methoxyindolediketopiperazines from Acrostalagmus luteoalbus,a Marine Algal Isolate of En
Four new N-methoxyindolediketopiperazines (acrozines D-G,1-4) and six known congeners (5-10) were purified from the orga......
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There are several reports of anti-tumor necrosis factor(TNF)-induced lung disease,especially in patients with rheumatolo......
How should immunomodulators be optimized when used as combination therapy with anti-tumor necrosis f
In the last 15 years the management of inflammatory bowel disease has evolved greatly,largely through the increased use ......
The optical characteristics of reduced glutathione molecules between 0.2 THz and 2.4 THz have been investigated by THz t......
The Tremadocian is the first stage of the Ordovician System and is subdivided into two parts in general. The Upper Trema......
In this paper, a novel approach termed process goose queue (PGQ) is suggested to deal with real-time optimization (RTO) ......
Worldwide sales of biologic drugs exceeded 100 billion USD in 2011.About 32% is from therapeutic monoclonal antibody(mAb......
Objective Cyclo-trans-4-L-hydroxyprolyl-L-serine(JBP485)is a dipeptide isolated from Laennec,and Laennec is a hydrolyzat......
Tumor necrosis factor-α inhibitors (anti-TNFs) are effective in the treatment of inflammatory bowel disease (IBD) recal......
Inflammatory rheumatic diseases frequently affect women of childbearing age.Biologic therapy during pregnancy is an impo......
Risk of hepatitis B virus reactivation in rheumatoid arthritis patients undergoing biologic treatmen
Hepatitis B virus(HBV) reactivation in rheumatoid arthritis(RA) patients undergoing biological therapy is not infrequent......
Rheumatoid arthritis is a chronic systemic inflammatory disease that often affects the cervical spine.While it was initi......
The management of rheumatoid arthritis(RA) in the past three decades has undergone a paradigm shift from symptomatic rel......
Tofacitinib is the first in a new class of nonbiologic disease-modifying antirheumatic drugs(DMARDs), a targeted, synthe......
Interstitial lung disease in rheumatoid arthritis:Current concepts in pathogenesis,diagnosis and the
Rheumatoid arthritis(RA) is the most common chronic autoimmune inflammatory joint disease. RA-associated interstitial lu......
Leptin,an adipokine responsible for body weight regulation,may be involved in pathological processesrelated to inflammat......
The Comparison of Biologic Characteristics between Mice Embryonic Stem Cells and Bone Marrow Derived
OBJECTIVE This research was to induce dendritic cells (DCs)from mice embryonic stem cells and bone marrow mononuclearcel......
INTRODUCTION Cell apoptosis,which involves the biologic regulation of the numbers and vital activity of cells,is an imp......
An increased cardiovascular morbidity and mortality, including the risk of sudden cardiac death(SCD), has been shown in ......
Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically inta
AIM:To establish a nude mice model of human hepatocellularcarcinoma(HCC)via orthotopic implantation of histologicallyin......
Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric ca
AIM:To investigate the expression of PTEN/MMAC_1/TEP_1and vascular endothelial growth factor(VEGF),their rolesin biolog......
In the Middle East, dust and sand storms are a persistent problem and can be inhaled into the mouth, nasal pharynx, and ......
In the Middle East, dust storms are a persistent problem and can be easily inhaled into the mouth, nasal pharynx, and lu......
Chemical coagulation is very important in water treatment, in which coagulant is an essential part. Pre-polymerized Al3+......
AIM: To study the relationship between microvessel density (MVD), telomerase activity and biological characteristics in ......
目的探讨小梁切除术联合生物羊膜植入或联合引流器植入术治疗原发性青光眼的效果及并发症。方法原发性青光眼125例(150眼)随机分成......
目的评估小梁切除术联合生物羊膜植入或联合交联透明质酸钠植入术治疗原发性青光眼的有效性。方法回顾性研究,抽取该院2016年5月至2......
INTRUDUCTIONSomemodelsofnudemicethatfreshhumancolorectalcarcinomatisueorcelsweresuccesfulytransplantedsubcuteneouslyhavebeenr...
INTRUDUCTIONSomemodelsofnudemicethatfreshhumancolorectalcarcinomatisueorcelsweresuccesfulytransplantedsubcuteneousl......
Collagen is the major acellcar of connective tissue protein in animals,accountingfor about 25% of the total body protei......
Appropriate selection of the implant biomaterial is a key factor for long term success of implants. The biologic environ......
[Objective] The study about the nitrogen releasing law of bamboo-charcoal coated urea and the biologic utilization effec......
Symbiotic nitrogen fixation of rhizobia and leguminous plants is considered as the most important biologic nitrogen fixa......
The administration of combination products in U.S.Food and Drug Administration(FDA)are analyzed and summarized in this p......
Elevation of liver biochemistry has been reported with anti-tumor necrosis factor agents, but overt liver failure rarely......
AIM To evaluate the possibility of usingcultured human hepatocytes as a bridge betweenbioartificial liver and liver tra......
Cholangiocytes-the epithelial cells which line the bileducts-are increasingly recognized as importanttransporting epith......
Proximal-distal motor unit number estimationdynamic changes in patients with amyotrophic lateral scl
BACKGROUND:Amyotrophic lateral sclerosis(ALS) is the most common of all the motor neuron diseases and the absence of a b......
Corticosteroids and immunomodulators have been the mainstay therapies for Crohn’s disease. Corticosteroids are highly e......
Inflammatory bowel disease (IBD) often affects women around the age of conception and pregnancy. Most drugs used to trea......
Infliximab (IFX) is currently the only biologic therapy used in the treatment of moderate-to-severe ulcerative colitis (......
Crohn’s disease (CD) is a chronic autoimmune disorder that affects mainly young people. The clinical management is base......
Clostridium difficile infection and inflammatory bowel disease:Understanding the evolving relationsh
Clostridium difficile(C.difficile)infection(CDI)is the leading identifiable cause of antibiotic-associated diarrhea.Whil......
Hepatitis B virus (HBV) reactivation represents an emerging cause of liver disease in patients undergoing treatment with......
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What is the best way to manage screening for infections and vaccination of inflammatory bowel diseas
The use of biological agents and immunomodulators for inflammatory bowel disease(IBD) is associated with an increased ri......
Multiple myeloma(MM),a malignancy of clonalplasma cells,is characterized by proliferation andaccumulation of abnormal p......
Fat-forming variant of solitary fibrous tumor(fat-forming variant of SFT), previously calledlipomatous hemangiopericyto......
~(18)F-FDG uptake as a biologic factor predicting outcome in patients with resected non-small-cell l
Background The outcome of surgical treatment of non-small-cell lung cancer (NSCLC) remains poor.In many patientsthe bio......
The incidence of inflammatory bowel diseases(IBD)is rising worldwide.The therapeutic options for IBD are expanding,and t......