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目的:观察高选择性1α受体阻滞剂对改善经尿道前列腺电切术(TURP)术后早期排尿状况的疗效并探讨其作用机制。方法:选40例良性前列腺增生症(BPH)的患者行TURP手术,术后第1天开始服用盐酸坦络新(0.2 m g/d晚睡前服),连续1个月。复测记录最大尿流率、膀胱剩余尿量、及IPSS评分。结果:该组病例上述三项指标均较TURP术后未服用高选择性α1受体阻滞剂的患者明显改善。结论:TURP术后早期服用高选择性1α受体阻滞剂对改善术后早期排尿状况有明显疗效。
Objective: To observe the curative effect of high selective 1α-blocker on improving early urination after transurethral resection of prostate (TURP) and to explore its mechanism. Methods: Forty patients with benign prostatic hyperplasia (BPH) underwent TURP. One day after starting the first day of operation, they took timolol hydrochloride (0.2 m g / d). Retest records the maximum flow rate, bladder residual urine volume, and IPSS score. Results: The above three indexes in this group of patients were significantly improved compared with those who did not take highly selective α1-blocker after TURP. Conclusion: TURP early use of highly selective 1Î ± receptor blockers to improve postoperative early urination have a significant effect.