本文报告了1986年间30例中国台湾人急性非淋巴细胞白血病(急非淋)的染色体研究结果及其和细胞形态学的联系。其中成人25例,儿童5例;年龄范围2～77岁,平均年龄为36岁;男性占43%,女性占57%;初诊患者22例,复发患者8例。染色体检查采用骨髓或外周血的直接制片法或不加丝裂原的短期培养法。标本经胰酶G显带技术处理后进行核型分析。结果20例(66%)显示克隆性染色体异常,其中2例仅有数目异常,18例则有结构重排。16例M_2中,7例有t(8;21)易位, This article reports the results of chromosomal studies on 30 cases of acute non-lymphocytic leukemia in China in 1986 and its association with cell morphology. Among them, there were 25 adults and 5 children; the age range was 2 to 77 years and the average age was 36 years; males accounted for 43%, and women accounted for 57%; 22 patients were newly diagnosed and 8 patients were relapsed. Chromosomal examinations were performed using either the direct method of bone marrow or peripheral blood or the short-term culture method without mitogen. Specimens were processed for karyotyping by trypsin G banding. Results Twenty cases (66%) showed chromosomal abnormalities, of which only 2 were abnormal and 18 had structural rearrangements. In 16 cases of M2, 7 cases had t(8;21) translocations.