Efficacy of anti-CD20 chimeric Fab’ fragment on proliferation of B lymphoma cells

来源 :中国科学通报：英文版 | 被引量 : 0次 | 上传用户：liuyu890501

【摘要】

：

The variable domain of heavy chain (VH) and light chain (VL) genes of anti-CD20 monoclonal antibody HL47 were cloned from anti-CD20 ScFv expression vector pCANB

【作者】

：

Lai ZZ Xiong DS Fan DM Xu

【机构】

：

ChineseAcadMedSci,BeijingUnionMedColl

【出处】

：

中国科学通报：英文版

【发表日期】

：

2001年14期

【关键词】

：

MONOCLONAL ANTIBODY CHIMERIC Fab’ B LYMPHOMA CD20. monoclonal antibody chimeric

【基金项目】

：

This work was supported by the State '863' High-Tech Project (Grant No. 102-09-03-03).

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The variable domain of heavy chain (VH) and light chain (VL) genes of anti-CD20 monoclonal antibody HL47 were cloned from anti-CD20 ScFv expression vector pCANBTEcd20 by PCR and ligated into vector pYZF to construct chimeric anti-CD20 Fab’ fragment expres

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Efficacy of anti-CD20 chimeric Fab’ fragment on proliferation of B lymphoma cells

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