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[目的]探讨签署治疗方案知情同意书对转移性肝癌患者治疗依从性的影响。[方法]通过问卷调查和随访调查,比较签署知情同意书(调查组)和未签署知情同意书患者(对照组)的遵医嘱执行情况、治疗完成情况、对治疗不良反应或并发症的认知理解程度、对主管医生和护士的信任程度及治疗依从性差异。[结果 ]调查组遵医嘱执行为好+中比例达98.4%,对照组为85.2%(χ2=14.855,P<0.01)。调查组治疗完成率为100%,对照组为90.7%,治疗完成率调查组显著高于对照组(χ2=10.200,P<0.01)。不良反应或并发症认知理解程度为好+中比例调查组达84.3%,对照组为67.6%(χ2=9.533,P<0.01)。对主管医生和护士的信任程度,调查组为好+中比例达96.8%,对照组为93.5%(χ2=3.43,P>0.05)。调查组治疗依从率达94.5%,明显高于对照组的83.1%(χ2=7.96,P<0.01)。[结论]签署治疗方案选择知情同意书可以提高转移性肝癌患者的遵医嘱执行率、对药物治疗的不良反应和手术治疗的并发症的认知和理解程度,提高其治疗依从性。
[Objective] To investigate the effect of signing the informed consent of the treatment regimen on the treatment compliance of patients with metastatic liver cancer. [Methods] Through the questionnaire survey and follow-up survey, we compared the execution of doctor’s order, the completion of treatment and the treatment of adverse reactions or complication of patients who signed the informed consent (investigation group) and the patients who did not sign the informed consent (control group) The level of understanding, the level of trust in the supervising doctors and nurses, and the differences in treatment adherence. [Results] The survey group performed well as doctor and the rate was 98.4% in control group and 85.2% in control group (χ2 = 14.855, P <0.01). The completion rate of the surveyed group was 100% and that of the control group was 90.7%. The treatment completion rate in the survey group was significantly higher than that in the control group (χ2 = 10.200, P <0.01). Adverse reactions or comprehension comprehension was good, with 84.3% in the median survey group and 67.6% in the control group (χ2 = 9.533, P <0.01). The degree of trust of the chief doctors and nurses was 96.8% in the survey group and 93.5% in the control group (χ2 = 3.43, P> 0.05). The compliance rate of the treatment group was 94.5%, significantly higher than 83.1% of the control group (χ2 = 7.96, P <0.01). [Conclusion] The signing of the treatment plan to choose informed consent form can improve the compliance rate of patients with metastatic liver cancer, the degree of cognition and understanding of the adverse reactions of medical treatment and the complications of surgical treatment, and improve the compliance of treatment.