头颈肿瘤淋巴结转移是导致患者预后差的主要原因。由于手术和放疗对此类转移的疗效不理想 ,对化疗又不敏感 ,故长期以来一直是头颈肿瘤治疗中的难题。为了研究探讨这一问题 ,本实验采用基因治疗与化疗相结合的方法 ,即导入基因后观察其耐药性的变化 ,以期为化学药物治疗头颈淋 Head and neck cancer lymph node metastasis is the leading cause of poor prognosis in patients. Due to the poor efficacy of surgery and radiotherapy for such metastases and the lack of sensitivity to chemotherapy, it has long been a challenge in the treatment of head and neck cancer. In order to study and discuss this problem, this experiment adopts the method of combining gene therapy with chemotherapy, that is to observe the change of drug resistance after introducing the gene, in order to treat the head and neck lymph