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目的探讨郑州地区无偿献血者乙型肝炎表面抗原(HBs Ag)的感染情况。方法选取2014年1月至2014年6月郑州地区96 820例无偿献血者作为研究对象,采用酶联免疫吸附试验(ELISA)检测HBs Ag。结果 18~25岁年龄组无偿献血者的HBs Ag阳性率最高,其次为25~35岁年龄组;城市无偿献血者的HBs Ag阳性率明显高于农村,差异有统计学意义(χ2=6.337,P<0.05)。结论低年龄城市无偿献血者的HBs Ag阳性率较高,为了控制乙型肝炎病毒的传播,应提高国内ELISA试剂的灵敏度,加强对无偿献血者HBs Ag阳性的筛查。
Objective To investigate the prevalence of hepatitis B surface antigen (HBsAg) in unpaid blood donors in Zhengzhou area. Methods A total of 96 820 unpaid blood donors in Zhengzhou area from January 2014 to June 2014 were selected as study objects, and HBsAg was detected by enzyme linked immunosorbent assay (ELISA). Results The positive rate of HBsAg in the blood donors from 18 to 25 years old was the highest, followed by that from 25 to 35 years old. The positive rate of HBsAg in urban blood donors was significantly higher than that in rural areas (χ2 = 6.337, P <0.05). Conclusion The positive rate of HBs Ag in blood donors in low-age urban areas is relatively high. In order to control the spread of hepatitis B virus, the sensitivity of domestic ELISA reagents should be raised and the HBsAg-positive screening should be strengthened.