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目的了解新生儿感染血培养细菌的分布及对抗生素敏感和耐药情况。方法用改良K-B法对感染性疾病新生儿血培养出的细菌进行药敏试验。结果普通血培养2781份,细菌检出率为1352%,其中金黄色葡萄球菌占3484%;L型血培养423份,检出率为1655%,其中L金黄色葡萄球菌占7000%,L表皮葡萄球菌占1857%。丁胺卡那霉素对金黄色葡萄球菌、表皮葡萄球菌、枯草杆菌、克雷伯杆菌及L金黄色葡萄球菌的敏感率分别为7938%、9091%、9200%、7895%和9183%;头孢氨噻肟对金黄色葡萄球菌、表皮葡萄球菌及克雷伯杆菌的敏感率分别为6565%、5714%和6842%;先锋霉素Ⅴ对表皮葡萄球菌的敏感率为7662%,对克雷伯杆菌的耐药率为8947%;庆大霉素和红霉素对枯草杆菌的敏感率分别为8933%和7333%;新青霉素Ⅱ对克雷伯杆菌、枯草杆菌、L金黄色葡萄球菌及L表皮葡萄球菌的耐药率分别为10000%、9333%、6735%和8462%;氨苄青霉素对枯草杆菌、表皮葡萄球菌和L表皮葡萄球菌的耐药率分别为8933%、7143%和7692%;青霉素对上述菌株耐药率均较高;复达?
Objective To understand the distribution of neonatal bacterial cultures of blood and the sensitivity and resistance to antibiotics. Methods The K-B method was used to test the antibacterial activity of bacteria in the neonatal blood of infectious diseases. Results There were 2781 common blood cultures with the detection rate of 1352%, of which Staphylococcus aureus accounted for 3484%; 423 Ltype blood cultures were detected with a detection rate of 1655% Accounting for 70 00%, Staphylococcus epidermidis accounting for 18 57%. The susceptibilities of amikacin to Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Klebsiella pneumoniae and Staphylococcus aureus were 7938%, 9091%, 9200%, 78 95% and 9183% respectively. The sensitivity rates of cefotaxime to Staphylococcus aureus, Staphylococcus epidermidis and Klebsiella were 6565%, 5714% and 6842%, respectively. Ⅴ was 7662% against Staphylococcus epidermidis and 8947% against Klebsiella pneumoniae. The sensitivities of gentamycin and erythromycin to Bacillus subtilis were 8933% and 7333%. The rates of resistance to penicillin Ⅱ to Klebsiella, Bacillus subtilis, Staphylococcus aureus L and Staphylococcus epidermidis were 10000%, 9333%, 6735% and 8453, respectively 62% respectively. The resistance rates of ampicillin to Bacillus subtilis, Staphylococcus epidermidis and Staphylococcus epidermidis were 8933%, 7143% and 7692, respectively ; Penicillin-resistant strains of the above-mentioned higher rates; re up to?