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Blumberg等1963年发现乙型肝炎表面抗原(HBsAg)以来,检测方法已经历3次技术换代:第一代系琼脂双向扩散法(AGD),因敏感度很低,目前已基本不用,第二代为对流免疫电泳法(CIEP),放射免疫对流电泳自显影法(RICEPA)等;第三代
Since the detection of hepatitis B surface antigen (HBsAg) by Blumberg et al in 1963, the detection method has undergone three technological changes: the first-generation agar two-way diffusion method (AGD) has basically no need due to its low sensitivity and the second generation is Convective immuno-electrophoresis (CIEP), radioimmunoassay (RICEPA) and so on; the third generation