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患儿女性,AIDS患者,其母亲的血清学阳性。5岁时出现癫痫大发作伴发热,但无皮疹,神经系统检查正常。CSF显示IgG指数增高,CT扫描正常。EEG示广泛的假性周期性异常伴右额顶区局灶性慢波。以后相继出现缄默、失语、睡眠倒错、和局灶性癫痫、意识模糊、脑膜刺激征、双侧Babinski征和抓握征阳性。能坐但不能站立行走,有感觉及运动障碍。血清P~(24)抗原滴度94pg/ml。EEG示左额叶弥漫性慢波伴痫性放电。CT扫描发现双侧额叶顶区低密度,MRI示双侧额枕区信号异常。予数种抗痫药物治疗无效,患儿逐渐发展为癫痫持续状态,病后2
Pediatric women, AIDS patients, their mothers are serologically positive. 5 years old, epileptic seizures with fever, but no rash, nervous system examination was normal. CSF showed IgG index increased CT scan was normal. EEG showed a wide range of pseudo-periodic abnormalities with right frontal focal focal slow wave. Later, there have been silence, aphasia, sleep inverted, and focal epilepsy, confusion, meningeal irritation, bilateral Babinski sign and grab sign positive. Can sit but can not stand walking, feeling and dyskinesia. Serum P ~ (24) antigen titer 94pg / ml. EEG shows diffuse slow wave of left frontal lobe with epileptiform discharge. CT scan revealed bilateral frontal lobe low density, MRI showed bilateral frontal occipital signal abnormalities. Several anti-epilepsy drugs to treat ineffective, children gradually developed into status epilepticus, 2