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生长激素 ( GH)是腺垂体合成和分泌的重要激素之一 ,由 1 91个氨基酸组成 ,具有刺激骨骼生长和促进代谢的作用。最近有资料表明 GH参与了心肌生长和心肌肥厚的调节〔1〕,并可能在心力衰竭( HF)的发生、发展和治疗中具有重要意义。现将这方面的研究进展综述如下。1 GH的生物学
Growth hormone (GH) is one of the important hormones in the synthesis and secretion of the pituitary gland. It consists of 191 amino acids and stimulates bone growth and promotes metabolism. Recent data suggest that GH is involved in the regulation of myocardial growth and cardiac hypertrophy [1] and may have important implications for the development, progression and treatment of heart failure (HF). Now the research progress in this area are summarized below. 1 GH biology