慢性乙型病毒性肝炎的病变类型及发展规律,国内外已有较深入的研究,但对部分疑难病例,单凭症状、体征、生化、酶谱及血清免疫指标确诊仍有困难。而该病的确诊和分型将直接影响病人的治疗及预后。为此,我们用光学显微镜、电子显微镜观察及HBsAg检测等方法对30例肝穿活检组织进行 Chronic hepatitis B lesions of the types and development of laws at home and abroad have been more in-depth study, but for some difficult cases, symptoms, signs, biochemical, zymogram and serum immune indicators still difficult to diagnose. The diagnosis and classification of the disease will directly affect the patient’s treatment and prognosis. To this end, we use optical microscopy, electron microscopy and HBsAg detection and other methods on the 30 cases of liver biopsy