IL-8是一种高效的嗜中性粒细胞激活蛋白,同时也是一种新的炎症刺激因子。不同细胞来源的IL-8,其N 末端氨基酸顺序互不相同,72肽和77肽的IL-8是它的两种主要形式。体内实验中两种IL-8没有明显的活性差异,而在体外,IL-8_(72)的生物学活性比IL-8_(77)的生物学活性强。文章采用了四种实验对72肽和77肽IL- IL-8 is a highly potent neutrophil activating protein and is also a novel inflammatory stimulator. IL-8 from different cell sources has a different N-terminal amino acid sequence, and IL-8 of the 72 peptide and the 77 peptide is its two major forms. In vivo, there was no significant difference in activity between the two IL-8s, whereas in vitro, the biological activity of IL-8 72 was stronger than that of IL-8 77. The article uses four experiments on the 72 peptide and 77 peptide IL-