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本实验采用一种改进的姐妹染色单体差别染色法,观察X线诱发离体人淋巴细胞姐妹染色单体互换率。以阐明细胞核内DNA损伤情况。实验结果表明,X线诱发人淋巴细胞的SCE频率与剂量有显著相关,并表现出良好的剂量——效应关系。
In this study, an improved sister chromatid difference staining method was used to observe the X-ray-induced sister chromatid exchange rate in human lymphocytes. To clarify the DNA damage in the nucleus. The experimental results show that the frequency of SCE induced by X-ray in human lymphocytes is significantly correlated with the dosage and shows a good dose-response relationship.